Nuclear and cytoplasmic expressions of ERb1 and ERb2 ar ...
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Nuclear and cytoplasmic express ...
Estrogen receptor (ER) a has been studied extensively in familial breast cancers but there are limited data on ERb and its isoforms. This is an impo ...
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Adjuvant dose-dense doxorubicin ...
Every-2-week (dose-dense) adjuvant doxorubicin (A) plus cyclophosphamide (C) followed by paclitaxel is a safe and effective adjuvant chemotherapy re ...
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S-adenosylhomocysteine hydrolas ...
Epigenetic abnormalities including abnormal histone methyltransferase activity contribute to breast cancer pathogenesis. An example is over expressi ...
612.15 KB
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Comparison of different approac ...
Human epidermal growth factor receptor 2 (HER2) testing is an essential part of pathological assessment in breast cancer patients, as HER2 provides ...
286.84 KB
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An evaluation of the clinical s ...
Studies in mice have shown that thymicderived CD4? CD25? regulatory T cells (T reg; FOXP3? lymphocytes) inhibit an antitumour immune response. Addi ...
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Involvement of MyoD and c-myb i ...
BRCA1 is closely related to the pathogenesis of breast cancer, BRCA1 mRNA is reduced in sporadic breast cancer cells despite the lack of mutations. ...
دانلود 1
896.15 KB
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Anti-tissue factor short hairpi ...
In breast cancer, there is a correlation between tissue factor (TF) expression, angiogenesis and disease progression. TF stimulates tumour angiogene ...
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Association between mitogen-act ...
Published data on the association between mitogen-activated protein kinase kinase kinase 1 (MAP3K1) gene rs889312 polymorphism and breast cancer ris ...
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Association of age and overall ...
We sought to determine if an association exists between age and capecitabine efficacy among patients with metastatic breast cancer (MBC). Pooled ana ...
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Estrogen receptor beta decrease ...
Estrogen receptor beta (ERb) inhibits proliferation in different cellular systems by regulating components of the cell cycle machinery. Eukaryotic c ...
815.26 KB
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CD4+ T cells inhibit the neu-sp ...
Studies conducted in animal model of infectious diseases or H-Y antigen model suggest a crucial role for CD4? T cells in providing help for CD8? T-c ...
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High serum TGF-a predicts poor ...
Lapatinib and capecitabine combination therapy is effective in trastuzumab-resistant human epidermal growth factor receptor 2 (HER2)-positive breast ...
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Results of a phase II study of ...
Palliation is the primary goal in metastatic breast cancer (MBC), and safe, efficacious, new singleagent options are needed. Pemetrexed, an antifola ...
233.82 KB
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Zoledronic acid prevents bone l ...
To determine whether zoledronic acid (ZA) can prevent bone loss in premenopausal women undergoing adjuvant chemotherapy for breast cancer. In this r ...
356.46 KB
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Phosphorylated S6K1 is a possib ...
Cross-talk between the estrogen receptor and the mammalian target of rapamycin (mTOR) pathway is one of the mechanisms of endocrine therapy resistan ...
371.86 KB
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Declining melatonin levels and ...
Serum melatonin (MLT) levels have been reported to diminish significantly by the 5th and 6th decades of life as the incidence of breast cancer incre ...
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Glycodelin expression associate ...
Glycodelin (encoded by PAEP gene) is a secreted lipocalin protein mainly expressed in reproductive tissues, but also in several tumour types. In the ...
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Genomics, histopathology, and t ...
Efforts to improve recurrence risk stratification for breast cancer patients have increasingly focused on rapidly developing gene expression profili ...
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Image-guided tumor resection us ...
Tumor involvement of resection margins is found in a large proportion of patients who undergo breastconserving surgery. Near-infrared (NIR) fluoresc ...
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Enhanced serine production by b ...
Since bone metastatic breast cancer is an incurable disease, causing significant morbidity and mortality, an understanding of the underlying molecul ...
500.10 KB
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Clinicopathologic and molecular ...
Akt/PKB serine/threonine kinase is a leading signalling modulator for several cellular processes including metabolism, growth, proliferation and sur ...
375.75 KB
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Distinct function of androgen r ...
Steroid receptor coactivators are important in regulating the function of the receptors in endocrine organ development and in cancers, including bre ...
1.70 MB
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Insulin like growth factor bind ...
Previously, we have shown that insulin-like growth factor binding protein-7 (IGFBP-7) expression is inversely correlated with disease progression in ...
750.15 KB
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Targeting trastuzumab-resistant ...
Targeting HER-2 over-expressing breast cancer cells with trastuzumab has resulted in significant improvements in both disease-free and overall survi ...
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Does radiotherapy planning with ...
This prospective study investigated radiation dose and volume changes during breathing cycle. Ten patients with left breast carcinoma receiving radi ...
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