Episcopic 3D Imaging Methods: Tools for Researching Gen ...
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Episcopic 3D Imaging Methods: T ...
This work aims at describing episcopic 3D imaging methods and at discussing how these methods can contribute to researching the genetic mechanisms dr ...
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Systems Behavior: Of Male Court ...
Male courtship in fruit flies is regulated by the same major regulatory genes that also determine general sexual differentiation of the animal. Elabo ...
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Post-Translational Control of S ...
Sp-family transcription factors are widely expressed in human tissues and involved in the regulation of many cellular processes and response to cellu ...
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Functional and Clinical Evidenc ...
We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas ( ...
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MicroRNA and Cancer: Tiny Molec ...
Cancer is currently a major public health problem and, as such, emerging research is making significant progress in identifying major players in its ...
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The Potential Role of Pharmacog ...
Although notable progress has been made in the treatment of non-small-cell lung cancer (NSCLC) in recent years, this disease is still associated with ...
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Genome Analysis of Food Grade L ...
Whole-genome sequencing has revolutionized and accelerated scientific research that aims to study the genetics, biochemistry and molecular biology of ...
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Plant Spliceosomal Introns: Not ...
Spliceosomal introns in higher eukaryotes are present in a high percentage of protein coding genes and represent a high proportion of transcribed nuc ...
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Computational Challenges of Per ...
It is widely predicted that cost and efficiency gains in sequencing will usher in an era of personal genomics and personalized, predictive, preventiv ...
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Can Systems Biology Understand ...
Cancer is thought to be caused by a sequence of multiple genetic and epigenetic alterations which occur in one or more of the genes controlling cell ...
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Genetic and Molecular Basis of ...
A systematic study has been conducted of all available reports in PubMed and OMIM (Online Mendelian Inheritance in Man) to examine the genetic and mo ...
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Clinical Utility of Microarrays ...
Microarray-based clinical tests have become powerful tools in the diagnosis and treatment of diseases. In contrast to traditional DNA-based tests tha ...
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Mass Spectrometry-Based Approac ...
Mass spectrometry has served as a major tool for the discipline of proteomics to catalogue proteins in an unprecedented scale. With chemical and meta ...
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Cause and Consequences of Genet ...
Both genetic and epigenetic changes contribute to development of human cancer. Oncogenomics has primarily focused on understanding the genetic basis ...
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Genetic Variation and Atheroscl ...
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying ...
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Oncogenomic Approaches in Explo ...
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signall ...
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How Drosophila melanogaster For ...
A strictly determined number of external sensory organs, macrochaetes, acting as mechanoreceptors, are orderly located on drosophila head and body. T ...
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Gene Polymorphisms and Pharmaco ...
Rheumatoid arthritis (RA) is a systemic, chronic and inflammatory disease of unknown etiology with genetic predisposition. The advent of new biologic ...
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Drosophila Lethal Giant Larvae ...
Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting pro ...
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Genetics and Molecular Biology ...
Tuberous Sclerosis Complex is a multisystem disorder exhibiting a wide range of manifestations characterized by tumour-like lesions called hamartomas ...
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Periostin as a Heterofunctional ...
Periostin (Postn) is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesi ...
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Salivary Genomics, Transcriptom ...
There is an increasingly growing interest world-wide for the genomics, transcriptomics and proteomics of saliva and the oral cavity, since they provi ...
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Application of TILLING and EcoT ...
With the fairly recent advent of inexpensive, rapid sequencing technologies that continue to improve sequencing efficiency and accuracy, many species ...
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Alternative Splicing and Tumor ...
Alternative splicing is a key molecular mechanism for increasing the functional diversity of the eukaryotic proteomes. A large body of experimental d ...
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Analysis of NCL Proteins from a ...
The Neuronal Ceroid Lipofuscinoses (NCLs) are the most common group of neurodegenerative disorders of childhood. While mutations in eight different g ...
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