Prognostic factor analysis of t ...
Background Almost all patients with advanced gastric cancer will eventually develop progressive disease after first-line chemotherapy. However, the ...
Does immigration play a role in ...
The observed increased risks of gastric cancer among first-generation immigrants compared to those in Swedes suggest the role of childhood environme ...
Prognostic relevance of demogra ...
Background Although studies comparing the surgical treatment of gastric carcinoma in Japan and Western industrialized countries have revealed differ ...
Caspase 8 and caspase 9 gene po ...
Background Caspase-8 (CASP8) and caspase-9 (CASP9) play crucial roles in regulating apoptosis, and their functional polymorphisms may alter cancer r ...
p53 codon 72 polymorphism in pa ...
Background The common p53 codon 72 polymorphism has been investigated as a risk factor for cancer in different populations; however, the results hav ...
Phase II study of weekly paclit ...
Background Our previous phase I study provided evidence that weekly paclitaxel, cisplatin, and bolus 5-fluorouracil (weekly PCF) was effective and w ...
Increased risk of tuberculosis ...
Background Gastrectomy for peptic ulcers and chemotherapy for malignancy are known risk factors for tuberculosis (TB). However, this relationship ha ...
A phase II study of biweekly mi ...
Background Preclinical studies have shown that mitomycin C (MMC) acts synergistically with irinotecan (CPT- 11). In this phase II study, we evaluate ...
IL-6 serum levels predict posto ...
Background Despite progress in surgical techniques and perioperative care, gastrectomy remains a procedure of significant morbidity. Several scoring ...
Human gastrin mRNA expression u ...
Background Helicobacter pylori-cytotoxin-associated protein A (CagA) and gastrin are believed to play an important role in gastric carcinogenesis, b ...
Functional outcomes according t ...
Background In gastric cancer, various methods of gastric resection and reconstruction have been devised according to the location of the primary tum ...
A small interfering RNA targeti ...
Background Accumulating evidence suggests that the tumor suppressor gene Kruppel-like factor 6 (KLF6) and its dominant-negative splice form KLF6-SV1 ...
Value of sentinel lymph node ma ...
Background Forty percent of patients with gastric cancer have unnecessarily extended lymph node dissections with higher rates of morbidity and morta ...
Evaluation of modified Estimati ...
Background We recently modified our prediction scoring system ‘‘Estimation of Physiologic Ability and Surgical Stress’’ and have designated the curr ...
Bacteremia and endotoxemia afte ...
Background Because the invasive procedure of endoscopic submucosal dissection (ESD) entails a large mucosal defect which is left open, with extensiv ...
Optimal indications of surgical ...
Background Decision-making for surgical palliation remains one of the most challenging clinical scenarios. We investigated the optimal indications f ...
Survival benefit of bursectomy ...
Background Bursectomy is regarded as a standard surgical procedure during gastrectomy for serosa-positive gastric cancer in Japan. There is little e ...
The delta-shaped anastomosis in ...
Background We developed a new method of intracorporeal gastroduodenostomy, the delta-shaped anastomosis, in which only endoscopic linear staplers ar ...
First-line fluorouracil-based c ...
Background Treatment with an oral fluoropyrimidine plus cisplatin is widely used for advanced gastric cancer, but patients with severe peritoneal me ...
Clinicopathological analysis fo ...
Background The prognosis for patients with stage Ib (second English edition of the Japanese classification of gastric carcinoma) gastric cancer is p ...
Decreased NKG2D expression on N ...
Background Although malignant diseases are known to be associated with immune suppression, the detailed mechanisms involved are still unknown. NKG2D ...
A multiple-center phase II stud ...
Background Docetaxel and oxaliplatin are active agents for advanced gastric cancer (GC). The combination of these two drugs in a triweekly schedule ...
Frequent development of leptome ...
We detected 7 cases of leptomeningeal carcinomatosis in 126 patients with peritoneal dissemination of gastric cancer who received combined systemic ...
Multicenter study of the long-t ...
Background Little information is available on the longterm outcomes of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in pati ...
Phase II trial of combined trea ...
Background To improve the poor prognosis in patients with stage IV (StIV) gastric cancer (GC), we conducted a multicenter phase II study of preopera ...