Molecular Mechanisms of Inherited Arrhythmias
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Cause of Chirality Consensus
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Molecular Mechanisms of Inherit ...
Inherited arrhythmias and conduction system diseases are known causes of sudden cardiac death and are responsible for significant mortality and morbi ...
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Recent Advances in the Characte ...
Human resistance to infection by schistosomes is associated to a strong Th2 immune. However a persistent Th2 response can cause severe kidney and liv ...
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Nutrigenomic Analysis of Diet-G ...
Recent advances in molecular biology combined with the wealth of information generated by the Human Genome Project have fostered the emergence of nut ...
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Toxicogenomics to Improve Compr ...
Engineered nanomaterials are commonly defined as materials with at least one dimension of 100 nanometers or less. Such materials typically possess na ...
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A Systematic Review of Meta-Ana ...
Background. Individual variations in gastric cancer risk have been associated in the last decade with specific variant alleles of different genes tha ...
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Multiple Hsp70 Isoforms in the ...
Hsp70 molecular chaperones play a variety of functions in every organism, cell type and organelle, and their activities have been implicated in a num ...
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Regulation of the Endoplasmic R ...
Calcium is a ubiquitous second messenger and is involved in virtually all cellular functions. Cellular events being regulated by calcium include gene ...
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Computational Approaches for Pr ...
A central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. Although missense variants are commonly i ...
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Cause of Chirality Consensus
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for l ...
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S100A8 and S100A9 Overexpressio ...
S100 protein A8 and A9 naturally form a stable heterocomplex. Recently, we have proved that S100A9 overexpression in various adenocarcinomas is assoc ...
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Ghrelin Regulates Insulin Relea ...
Insulin release from pancreatic islet ..-cells is stimulated by glucose. Glucose-induced insulin release is potentiated or suppressed by hormones and ...
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Targeting RSK: An Overview of S ...
Ribosomal S6 kinase (RSK) is a family of serine/threonine kinases that has been identified as a promising anti-cancer target. While a number of prote ...
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Inhibition of Protein Kinase c- ...
c-Src is a proto-oncogene involved in the genesis of and invasion by many cancers. This non-receptor tyrosine kinase also plays a crucial role in bon ...
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Runx1/AML1 is a Guardian of Hem ...
An oncogenic stimulus in a cell primarily results in hyperproliferation. However, uncontrolled cell proliferation is sensed by the cell and triggers ...
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Genome Annotation in Plants and ...
In this era of whole genome sequencing, reliable genome annotations (identification of functional regions) are the cornerstones for many subsequent a ...
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Metabotropic Glutamate Receptor ...
Multiple in vivo and in vitro studies show that excessive release of glutamate, and subsequent activation of ionotropic glutamate receptors (iGluRs) ...
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Assembly of the Asparagine- and ...
The proteins Ure2, Sup35 and Rnq1 from the baker’s yeast have infectious properties, termed prions, at the origin of heritable and transmissible phen ...
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The Protein Kinase Inhibitor Ba ...
Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncolo ...
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Development of Non-Nucleoside R ...
The NNRTIs play an important role in the present therapy against HIV/AIDS. This review discusses the basic principles in the development of NNRTIs fo ...
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Role of Mismatch Repair and MGM ...
Tumor resistance to cytotoxic chemotherapy drugs and their toxicity to normal cells are major clinical obstacles to anticancer therapy effectiveness. ...
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Influence of Enzyme-Inducing An ...
Background: Imatinib mesylate is used in combination with hydroxyurea (HU) in ongoing clinical phase II studies in recurrent glioblastoma multiforme ...
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Rapid Screening of Toxigenic Vi ...
The ability to sensitively detect Vibrio cholera with PCR-ELISA method represents a considerable advancement over alternative more time-consuming met ...
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Identification of Salmonella en ...
Salmonella enterica serovar Typhi is a human pathogenic microorganism with a very complex infective cycle, involving the transit of bacteria across d ...
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Genome Annotation in Plants and ...
In this era of whole genome sequencing, reliable genome annotations (identification of functional regions) are the cornerstones for many subsequent a ...
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INVESTIGATION OF DEEP STERNAL W ...
Objective: To investigate factors that predict sternal wound complications in patients after coronary artery bypass grafting (CABG) because predictio ...
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