Inhibition of Phosphodiesterases Leads to Prevention of ...
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LOX-1 Transcription
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Inhibition of Phosphodiesterase ...
(PDEs) with IBMX (1-methyl-3-isobutylxanthine) can modulate the mitochondrial permeability transition pore (mPTP) opening by inactivating glycogen s ...
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Chronic Istaroxime Improves Car ...
exerts inotropic action by reducing Na+/K+-ATPase activity, and simultaneously it stimulates sarcoplasmic reticulum Ca2+-ATPase function, thus also ...
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Heart Protection by Combination ...
lateischemia/ early reperfusion therapy with the â1-adrenergic receptor (AR) blocker esmolol and phosphodiesterase III inhibitor milrinone reduced ...
دانلود 1
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Cardioprotective Effect of 3-Io ...
3-iodothyronamine (T1AM) is an endogenous compound which shares structural and functional features with biogenic amines and is able to interact with ...
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The Role of β-adrenergic Recept ...
Aim To determine the mechanism whereby transient stimulation of the â-adrenergic receptor subtypes (â-AR) elicit cardioprotection against subsequent ...
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Age Related Issues in Reperfusi ...
Advances in pharmacological treatment and effective early myocardial revascularization have led to improved clinical outcomes in patients with acute ...
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Protection of Endothelial Cells ...
Aims It is generally accepted that the oxidative stress and the proliferative activity of vascular smooth muscle cells (VSMCs) contribute to the pat ...
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Effect of Aliskiren in Patients ...
Aims To compare the effect of the direct renin inhibitor aliskiren on neurohumoral activity in heart failure patients treated with low-dose and high ...
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Achievement of Lipid Targets wi ...
Objective The objective of this study was to assess the proportion of patients with type 2 diabetes mellitus (T2DM) attaining individual and combine ...
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Reduced Thrombin Generation and ...
Purpose The objective of our study was to identify changes in the coagulation and serum concentration of soluble P-selectin (sP-sel) after i.v. bolu ...
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The Impact of Age on Effects of ...
Purpose Glycoprotein IIb/IIIa inhibitors are favourable in ST-elevation myocardial infarction (STEMI) patients, and the additional value of early pr ...
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An Introduction to Small Non-co ...
Research into small non-coding RNAs (ncRNA) has fundamentally transformed our understanding of gene regulatory networks, especially at the post-tran ...
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Polymorphisms of the Beta Adren ...
Purpose Prior studies demonstrate an association between specific beta-adrenergic receptor (â-AR) polymorphisms and clinical outcomes in patients wi ...
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LOX-1: A New Target for Therapy ...
Abstract There is much interest in the role of oxidant stress in an ever-increasing list of disease states. However, the precise mediator of oxidant ...
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The Discovery of LOX-1, its Lig ...
LOX-1 is an endothelial receptor for oxidized low-density lipoprotein (oxLDL), a key molecule in the pathogenesis of atherosclerosis.The basal expre ...
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LOX-1 Transcription
The importance of the lectin-like oxidized LDL receptor (LOX-1) gene in cardiovascular and other diseases is slowly being revealed. LOX-1 gene expre ...
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Abdominal Surgical Incision Ind ...
Objective Recently, a novel observation was made in which nonischemic trauma at a site remote from the heart produced by a transverse abdominal inci ...
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Efficacy of Ivabradine in Combi ...
Purpose The antianginal and anti-ischemic efficacy of the selective If inhibitor ivabradine is established in patients with stable angina in monothe ...
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Prospective Cohort Study of Gas ...
Objective Although aspirin has been widely prescribed for the prevention of cardiovascular events, its risk of gastrointestinal complications is of ...
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Novel Sequencing-based Strategi ...
Human inherited antibody deficiency disorders are generally caused by mutations in genes involved in the pathways regulating B-cell class switch rec ...
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Aggravation of diabetic nephrop ...
Objective To clarify whether the induction of Thy-1.1 nephritis aggravates diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat ...
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Hepatocarcinogenesis: imaging-p ...
Rapid advances in liver surgery, including liver transplantation, radiology, and pathology, have created a need for clinically relevant nomenclature ...
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Internal hernias after abdomina ...
As less-invasive treatments for small bowel obstruction, such as laparoscopic surgery or small incision therapy, have become common, there is a grow ...
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Petersen’s hernia as a complica ...
Referrals for bariatric surgery have currently increased due to the need for more effective interventions in the management of severely obese patien ...
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Guest editor’s introduction: He ...
These review articles will enhance the knowledge of radiologists about current imaging modalities and various contrast agents for the detection and ...
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