Treatment of child obesity
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Leukemia stem cells
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Treatment of child obesity
Prevention of obesity should have the highest priority and be started as early in life as possible in high-risk families. This review covers the m ...
110.56 KB
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Application of DEXA in body co ...
Clinical and research applications of dual-energy X-ray absorptiometry in childhood are reviewed. Originally used for bone mineralization assessme ...
69.33 KB
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Proliferation and differentiati ...
CD34 is the most frequently used marker for the selection of cells for bone marrow (BM) transplantation. The use of CD133 as an alternative marker i ...
365.04 KB
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Iron overload in MDS—pathophysi ...
Many patients with myelodysplastic syndromes (MDS) become dependent on blood transfusions and develop transfusional iron overload, which is exacerba ...
367.32 KB
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Leukemia stem cells
Leukemia-initiating cells (LICs) or leukemia stem cells (LSCs) are defined by their ability to form tumors after xenotransplantation in immunodefici ...
813.02 KB
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Anemia—still a major health pro ...
Anemia is a major global health problem, especially in developing countries. This fundamental health issue still has not been solved and continues t ...
167.12 KB
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CD44 in hematological neoplasia ...
The CD44 protein family spans a large group of transmembrane glycoproteins acquired by alternative splicing and post-translational modifications. Th ...
دانلود 1
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Expansion of CD4+CD25+ regulato ...
Rapamycin has important roles in the modulation of regulatory T cells. We tried to expand CD4+CD25+ regulatory T cells (Treg cells) from umbilical c ...
269.55 KB
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Quantitative analysis of Hb Bar ...
It has long been recognized that the presence of hemoglobin (Hb) Bart’s in newborn’s blood is associated with α-thalassemia. However, the automated ...
311.20 KB
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Prolonged transendothelial migr ...
The therapeutic success of haematopoetic stem and progenitor cell (HSPC) transplantation is critically dependent on HSPC engraftment in the bone mar ...
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The impact of treatment, socio- ...
Cancer survivors are at risk of experiencing adverse physical and psychosocial effects of their cancer and its treatment. Both Hodgkin’s lymphoma (H ...
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Formation of an adherent hemato ...
Expansion of transplantable cord blood (CB) progenitors using a stroma requires provision of an exogenous cell source because of the low frequency o ...
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Deferasirox effectively decreas ...
Iron overload is present in several cases of double heterozygous sickle-cell/beta-thalassemia (HbS/β-thal). Deferasirox is an orally administered ir ...
136.38 KB
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Dysmetabolic hyperferritinemia ...
Hyperferritinemia is common in individuals with the metabolic syndrome (dysmetabolic hyperferritinemia), but its pathophysiology and the degree to w ...
99.71 KB
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Myeloid growth factors in acute ...
Randomized controlled trials (RCT) investigating administration of colony-stimulating factors (CSF) during or after chemotherapy in acute myeloid le ...
404.43 KB
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Hydralazine and magnesium valpr ...
Decitabine and azacitidine, two DNA methyltransferase (DNMT) inhibitors, are the current standard of treatment for myelodysplastic syndrome (MDS). H ...
220.92 KB
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Oxidative stress contributes to ...
In the present study, we questioned the role of oxidative stress in hereditary spherocytosis (HS), where red blood cells (RBC) have a shortened surv ...
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A prospective study to assess t ...
This prospective study was carried out to assess the usefulness of five laboratory tests in the diagnosis of hereditary spherocytosis (HS), based on ...
دانلود 1
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Enhanced activation of autophag ...
Erythropoiesis in β-thalassemia patients is ineffective, primarily because of death of the erythroid progenitor cells at the polychromatic normoblas ...
866.43 KB
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Bone marrow mesenchymal stem ce ...
Adoptive cellular immunotherapy is an important treatment to eliminate residual tumor cells after hematopoietic stem-cell transplantation. Bone marr ...
764.48 KB
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Staurosporine induces megakaryo ...
The induction of megakaryocyte (MK) differentiation is a potent strategy for the clinical treatment of diseases related to blood platelet disorders. ...
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Cost-effectiveness of adenotons ...
In children with sickle cell disease (SCD), adenotonsillar hypertrophy or recurrent tonsillitis are frequently linked with an increased risk of obst ...
128.78 KB
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Molecular characterization of a ...
Over 80% of the α-thalassemia cases in southern China are caused by large deletions involving the α-globin gene cluster on chromosome 16p13.3. Here, ...
311.81 KB
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Leukemias induced by altered TR ...
Rapamycin is a potent allosteric mTORC1 inhibitor with clinical applications as an anticancer agent. However, only a fraction of cancer patients res ...
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The role of zinc protoporphyrin ...
The differentiation between primary myelofibrosis (PMF) and essential thrombocythaemia (ET) may be difficult especially in early-stage disease. In P ...
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