Cardioprotection by mild hypothermia during ischemia in ...
رایگان
Cardioprotection by mild hypoth ...
Cooling the ischemic heart by just a few degrees protects it from infarction without affecting its mechanical function, but the mechanism of this pr ...
522.02 KB
رایگان
Activated NHE1 is required to i ...
The Na?/H? exchanger isoform 1 (NHE1) has been implicated as being causal in cardiac hypertrophy and the protein level and activity are elevated in ...
دانلود 1
517.85 KB
رایگان
Oxidative stress-induced format ...
Shortly after birth, mammalian cardiomyocytes irreversibly exit from the cell cycle and become terminally differentiated. The cellular mechanisms re ...
1.01 MB
رایگان
Expression of mitochondrial fus ...
Studies on the role of mitochondrial fission/ fusion (MFF) proteins in the heart have been initiated recently due to their biological significance i ...
562.94 KB
رایگان
Effect of PAR2 in regulating TN ...
Protease-activated receptor-2 (PAR2) is expressed in endothelial cells and mediates endotheliumdependent vasodilation. We hypothesized that PAR2 reg ...
880.27 KB
رایگان
Differential chemokine receptor ...
Postnatal vasculogenesis is mediated by endothelial progenitor cells (EPCs) which consist of subpopulations with different functional capacities. Ou ...
دانلود 1
317.02 KB
رایگان
Pioglitazone limits myocardial ...
Pioglitazone (PIO), a PPAR-c agonist, limits myocardial infarct size by activating Akt and upregulating cytosolic phospholipase A2 (cPLA2) and cyclo ...
962.69 KB
رایگان
Desmoglein 2 mutant mice develo ...
Desmosomes are cell–cell adhesion sites and part of the intercalated discs, which couple adjacent cardiomyocytes. The connection is formed by the ex ...
2.03 MB
رایگان
In vitro epithelial-to-mesenchy ...
Adult epicardial cells are required for endogenous cardiac repair. After myocardial injury, they are reactivated, undergo epithelial-to-mesenchymal ...
2.65 MB
رایگان
Expression of IL-17A in human a ...
A chronic (auto)immune response is the critical mechanism in atherosclerosis. Interleukin-17A is a pivotal effector cytokine, which modulates immune ...
500.75 KB
رایگان
Exercise-induced modulation of ...
Cardiac lipid accumulation is associated with decreased cardiac function and energy status (PCr/ATP). It has been suggested that elevated plasma fat ...
346.10 KB
رایگان
A high fat diet increases mitoc ...
Elevated levels of cardiac mitochondrial uncoupling protein 3 (UCP3) and decreased cardiac efficiency (hydraulic power/oxygen consumption) with abn ...
435.32 KB
رایگان
The alpha1 isoform of soluble g ...
Nitric oxide (NO)-dependent soluble guanylate cyclase (sGC) activation is an important component of cardiac signal transduction pathways, including ...
415.87 KB
رایگان
Intracoronary administration of ...
A model of intracoronary stem cell delivery that enables transgenesis/gene targeting would be a powerful tool but is still lacking. To address this ...
1.26 MB
رایگان
Remote postconditioning by humo ...
Short non-lethal ischemic episodes administered to hearts prior to (ischemic preconditioning, IPC) or directly after (ischemic postconditioning, IPo ...
519.59 KB
رایگان
Deficiency in TIMP-3 increases ...
Cardiac rupture is a fatal complication of myocardial infarction (MI); however, its underlying molecular mechanisms are not fully understood. This s ...
540.89 KB
رایگان
Intravenous and intramyocardial ...
Congestive heart failure developing after acute myocardial infarction (AMI) is a major cause of morbidity and mortality. Clinical trials of cell-bas ...
815.06 KB
رایگان
Effect of sulfur dioxide precon ...
Sulfur dioxide has recently been found to be produced endogenously in the cardiovascular system and have important positive biological effects. Howe ...
804.09 KB
رایگان
Diabetes mellitus abrogates ery ...
Recent studies reported cardioprotective effects of erythropoietin (EPO) against ischemia–reperfusion (I/R) injury through activation of the reperfu ...
1.10 MB
رایگان
Paraventricular nucleus cortico ...
Recent studies indicate that systemic administration of tumor necrosis factor (TNF)-a induces increases in corticotrophin releasing hormone (CRH) an ...
566.04 KB
رایگان
Prevalence of intimal heat shoc ...
Heat shock proteins (HSPs) are among the most highly conserved and immunogenic proteins shared by microbial agents and mammals. Human (h) HSP60 is ...
525.77 KB
رایگان
Opposing effects of monomeric a ...
C-reactive protein (CRP) has been linked to the pathogenesis of atherosclerosis. The dissociation of native, pentameric (p)CRP to monomeric (m)CRP o ...
دانلود 1
858.05 KB
رایگان
Clopidogrel improves endothelia ...
Clopidogrel treatment in patients with coronary artery disease not only inhibits platelet activation but also improves endothelial function and nitr ...
411.89 KB
رایگان
Mitogen-activated protein kinas ...
Current available biomarkers cannot identify myocardial ischemia without necrosis. To overcome this issue and to increase diagnostic power, we evalu ...
757.62 KB
رایگان
Effects of high thoracic epidur ...
High thoracic epidural anesthesia (HTEA) blocks the afferent and efferent cardiac sympathetic nerve fibers and may affect atrial electrophysiologica ...
849.67 KB
رایگان
