High serum TGF-a predicts poor response to lapatinib an ...
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High serum TGF-a predicts poor ...
Lapatinib and capecitabine combination therapy is effective in trastuzumab-resistant human epidermal growth factor receptor 2 (HER2)-positive breast ...
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Inflammatory breast cancer: hig ...
Inflammatory breast cancer (IBC), the most lethal form of breast cancer, has characteristics linked to higher risk of contralateral breast cancer. H ...
253.07 KB
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CD4+ T cells inhibit the neu-sp ...
Studies conducted in animal model of infectious diseases or H-Y antigen model suggest a crucial role for CD4? T cells in providing help for CD8? T-c ...
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Topoisomerase II alpha protein ...
Overexpression of topoisomerase II protein (topo 2a) is postulated to be more closely associated with responsiveness to anthracycline-containing che ...
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Estrogen receptor beta decrease ...
Estrogen receptor beta (ERb) inhibits proliferation in different cellular systems by regulating components of the cell cycle machinery. Eukaryotic c ...
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Association of age and overall ...
We sought to determine if an association exists between age and capecitabine efficacy among patients with metastatic breast cancer (MBC). Pooled ana ...
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Association between mitogen-act ...
Published data on the association between mitogen-activated protein kinase kinase kinase 1 (MAP3K1) gene rs889312 polymorphism and breast cancer ris ...
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A phase I clinical and pharmaco ...
Vinfunine (VFL) is a novel bifluorinated tubulin-targeted agent of the vinca alkaloids class active in advanced stage breast cancer. We conducted a ...
دانلود 1
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Anti-tissue factor short hairpi ...
In breast cancer, there is a correlation between tissue factor (TF) expression, angiogenesis and disease progression. TF stimulates tumour angiogene ...
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Involvement of MyoD and c-myb i ...
BRCA1 is closely related to the pathogenesis of breast cancer, BRCA1 mRNA is reduced in sporadic breast cancer cells despite the lack of mutations. ...
دانلود 1
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An evaluation of the clinical s ...
Studies in mice have shown that thymicderived CD4? CD25? regulatory T cells (T reg; FOXP3? lymphocytes) inhibit an antitumour immune response. Addi ...
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Comparison of different approac ...
Human epidermal growth factor receptor 2 (HER2) testing is an essential part of pathological assessment in breast cancer patients, as HER2 provides ...
286.84 KB
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S-adenosylhomocysteine hydrolas ...
Epigenetic abnormalities including abnormal histone methyltransferase activity contribute to breast cancer pathogenesis. An example is over expressi ...
612.15 KB
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Adjuvant dose-dense doxorubicin ...
Every-2-week (dose-dense) adjuvant doxorubicin (A) plus cyclophosphamide (C) followed by paclitaxel is a safe and effective adjuvant chemotherapy re ...
199.21 KB
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Long-term quality of life after ...
Population-based studies on quality of life (QOL) of long-term breast cancer survivors are quite recent and insufficient attention has been paid to ...
474.46 KB
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Nuclear and cytoplasmic express ...
Estrogen receptor (ER) a has been studied extensively in familial breast cancers but there are limited data on ERb and its isoforms. This is an impo ...
253.96 KB
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Effects of music therapy on pai ...
Music therapy has been used in multiple health care settings to reduce patient pain, anxiety, and stress. However, few available studies have invest ...
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Safety of zoledronic acid and i ...
The AZURE trial is an ongoing phase III, academic, multi-centre, randomised trial designed to evaluate the role of zoledronic acid (ZOL) in the adju ...
338.69 KB
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The impact of an aromatase inhi ...
Aromatase inhibitors (AIs) have become the standard adjuvant therapy of postmenopausal breast cancer survivors. AIs induce a reduction of bioavailab ...
261.46 KB
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Family history of breast cancer ...
Triple-negative breast cancer accounts for less than 20% of breast cancers overall, but is the predominant subtype among carriers of mutations in BR ...
196.08 KB
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Change in blood flow velocity d ...
The aim of this study was to evaluate the arterial and venous blood flow in women who underwent upper limb axillary dissection surgery for the treat ...
دانلود 1
182.43 KB
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Proliferating macrophages assoc ...
Macrophages, a key cell in the inflammatory cascade, have been associated with poor prognosis in cancers, including breast cancer. In this study, we ...
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Coexpression of atypical chemok ...
Some evidence suggests that atypical chemokine binders (ACBs) including DARC, D6, and CCX-CKR play an important role in inhibiting invasion and meta ...
1.53 MB
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Monitoring of neoadjuvant chemo ...
We prospectively investigated using advanced magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) to ident ...
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Comprehensive genetic character ...
Germline mutations in the BRCA1/2 genes account for the majority of hereditary breast ovarian cancer (HBOC). Identification of causal mutations may ...
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