Daintain/AIF-1 promotes breast ...
Tumor-associated macrophages can release a vast diversity of growth factors, proteolytic enzymes, cytokines, and inflammatory mediators. Many of the ...
Deoxycytidine kinase is overexp ...
Only a minority of breast cancer patients responds to chemotherapy and we lack predictive biomarkers that help to select a patient-tailored therapy ...
MicroRNA profiles of healthy ba ...
In order to determine the microRNA expression pattern in normal basal and luminal breast epithelium and to analyze the relationship of this expressi ...
Final overall survival results ...
The ATHENA study expanded on the safety and efficacy data derived from first-line trials of bevacizumab combined with standard chemotherapy for loc ...
Molecular and epidemiological c ...
Inflammatory breast cancer (IBC) shows a high incidence in Tunisia and Egypt but epidemiological and molecular characteristics have not been describ ...
Differential expression of arre ...
Emerging evidence has implicated G proteincoupled receptors, such as CXCR4 and PAR2, in breast cancer progression and the development of metastatic ...
Membrane localization of insuli ...
Recent studies have identified a role for insulin receptor substrate-2 (IRS-2) in promoting motility and metastasis in breast cancer. However, no pu ...
Oral administration of benzyl-i ...
Benzyl-isothiocyanate (BITC) is a hydrolysis product of glucotropaeolin, a compound found in cruciferous vegetables, and has also been shown to have ...
Acquisition of metastatic tissu ...
Biopsies of metastatic tissue are increasingly being performed. Bone is the most frequent site of metastasis in breast cancer patients, but bone rem ...
The associations between two po ...
The association between single-nucleotide polymorphisms (SNPs) in the interleukin-10 (IL-10) gene promoter and breast cancer risk is still ambiguous ...
Locally advanced breast cancers ...
Interval cancers (ICs), defined as cancers detected between regular screening mammograms, have been shown to be of higher grade, larger size, and as ...
Genetic predictors of taxane-in ...
Taxanes have resulted in improved survival for breast cancer patients, but often cause neurological toxicities. Identification of biomarkers related ...
The effect of delays in treatme ...
It is generally accepted that delay in receiving treatment for breast cancer results in adverse outcomes. The purpose of this study was to evaluate ...
MDM2 SNP309 and TP53 R72P assoc ...
The aim of this study was to investigate the association of two genetic polymorphisms, MDM2 SNP309 and TP53 R72P, with incidence of neutropenia in b ...
Metabotropic glutamate receptor ...
Metabotropic glutamate receptors are G-protein- coupled receptors normally expressed in the central nervous system where they mediate neuronal excit ...
Five-year patterns of adjuvant ...
Adjuvant hormonal therapy (HT) for breast cancer improves survival, yet studies have shown that early discontinuation and suboptimal adherence are c ...
The tamoxifen metabolite norend ...
To improve the treatment of breast cancer, there has been a need for alternative aromatase inhibitors (AIs) that bring about adequate aromatase inhi ...
Circulating free DNA: a new sur ...
Despite progress made in the oncologic therapy, the prognosis of the patients with breast cancer is still limited by metastatic relapse often many y ...
Elimination of the chemotherapy ...
Metastatic breast cancer is currently incurable despite initial responsiveness, assumingly due to the presence of chemoresistant subpopulations that ...
PH006, a novel and selective Sr ...
The central role of Src in tumor progression and metastasis has validated it as an attractive therapeutic target for the treatment of human breast c ...
Prediction of lymph node involv ...
The aim of this study was to investigate whether lymph node involvement in breast cancer is influenced by gene or miRNA expression of the primary tu ...
ER, HER2, and TOP2A expression ...
At recurrence of breast cancer, the therapeutic target is the metastases. However, it is current practice to base the choice of systemic treatment o ...
Association between polymorphis ...
The renin–angiotensin system (RAS) has been considered to be implicated in the development of breast cancer. However, the results are inconsistent. ...
Increased risk for distant meta ...
The identification of women with early-stage breast cancer who will develop distant metastasis may improve clinical management. The transcriptional ...
Associations between polymorphi ...
We read with great interest the article by Yang et al. which investigated the associations between tumor necrosis factor-a (TNF-a) polymorphisms an ...