COX2 overexpression is a prognostic marker for Stage II ...
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COX2 overexpression is a progno ...
To determine the significance of (Cyclooxygenase 2) COX2 for clinical outcome in breast cancer, we analyzed the correlation between COX2 overexpress ...
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FOXA1 is an independent prognos ...
Forkhead box protein A1 (FOXA1) is a ‘‘pioneer factor’’ that plays a role in controlling nearly 50% of estrogen receptor target genes. FOXA1 express ...
434.05 KB
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Hematogenous and lymphatic tumo ...
Tumor cell dissemination in bone marrow (BM) and lymph nodes is considered an important step in systemic disease progression and is associated with ...
400.88 KB
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miRNA-34a is associated with do ...
Docetaxel is a chemotherapy drug to treat breast cancer, however as with many chemotherapeutic drugs resistance to docetaxel occurs in 50% of patien ...
407.02 KB
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Breast cancer and spider telang ...
Angiogenesis is one of the hallmarks of breast cancer. The status of angiogenesis is important in therapy choice. Spider telangiectasias (telangiect ...
281.75 KB
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Enhancement of chemotherapeutic ...
A subset of primary breast cancers and breast cancer cell lines express a hypermethylation defect (characterized by DNMT hyperactivity and DNMT3b ov ...
639.94 KB
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IL-15 and IL-2 increase Cetuxim ...
Triple negative breast cancer (TNBC) patients are not likely to benefit from anti-estrogen or anti-HER2 therapy and this phenotype is associated wit ...
656.49 KB
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Prognostic significance of meth ...
Free circulating DNA is increased in the serum/ plasma of cancer patients, and methylation of certain genes has been found to be characteristic for ...
341.30 KB
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Role of CD200 expression in reg ...
Previous studies have confirmed that levels of CD200 expression on the cells of the transplantable EMT6 mouse breast cancer line are increased marke ...
472.22 KB
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High-resolution genomic profili ...
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characte ...
821.62 KB
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Gene expression profiling of br ...
Microtubule-targeting agents, including taxanes (Tax) and ixabepilone (Ixa), are important components of modern breast cancer chemotherapy regimens, ...
649.62 KB
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Risk factors for lymphedema in ...
Risk factors for lymphedema and related arm symptoms in breast cancer (BC) survivors have not been examined using a large prospective population-bas ...
214.97 KB
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A gene transcription signature ...
Obesity is thought to contribute to worse disease outcome in breast cancer as a result of increased levels of adipocyte-secreted endocrine factors, ...
703.37 KB
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Assessing the RNA effect of 26 ...
Comprehensive genetic testing of the breast cancer susceptibility genes BRCA1 and BRCA2 identified approximately 16% of variants of unknown signific ...
847.50 KB
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Correlation between docetaxel-i ...
Steroids and H2 blockers are commonly used as supportive care for taxane-containing chemotherapy, but they also affect docetaxel’s primary metaboliz ...
236.79 KB
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The anatomy of fluid-yielding d ...
The concept of an intraductal approach to evaluate the breast microenvironment assumes direct access to the cancer-containing duct. Central duct acc ...
1,005.29 KB
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Prognostic significance of gene ...
The association between promoter methylation status and survival was investigated in a large cohort of women with breast cancer, participants in the ...
284.80 KB
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Oxidative stress and hematologi ...
Several adverse effects of chemotherapy treatments have been described, and most of these effects are associated with direct interactions between bl ...
450.36 KB
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Risk factors by molecular subty ...
Differences in incidence, prognosis, and treatment response suggest gene expression patterns may discern breast cancer subtypes with unique risk fac ...
226.35 KB
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The peptide-hormone glucagon-li ...
The incretin hormone glucagon-like peptide (GLP)-1 is secreted from intestinal L cells in response to food intake, and promotes insulin secretion an ...
714.23 KB
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Estrogen receptor-a and sex ste ...
Toll-like receptor 9 (TLR9) is a cellular DNAreceptor, which is widely expressed in cancer. Synthetic TLR9-ligands induce cancer cell invasion in vi ...
570.01 KB
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Detection of aberrant promoter ...
Aberrant promoter methylation of genes is a common molecular event in breast cancer. Thus, DNA methylation analysis is expected to be a new tool for ...
306.05 KB
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Detection of aberrant promoter ...
Aberrant promoter methylation of genes is a common molecular event in breast cancer. Thus, DNA methylation analysis is expected to be a new tool for ...
553.25 KB
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Second primary breast, endometr ...
Breast cancer incidence increases with age and exhibits a Black-to-White crossover around age 45. Breast cancer survivors are at a significantly ele ...
261.91 KB
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The effect of system-level acce ...
Treatment decisions associated with ductal carcinoma in situ (DCIS), including the decision to undergo breast reconstruction, may be more problemati ...
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