Primary tumor classification ac ...
Breast cancer patients with similar clinical stage may experience different disease outcomes. Aberrant DNA methylation of primary breast tumors can ...
bc-GenExMiner: an easy-to-use o ...
Gene prognostic meta-analyses should benefit from breast tumour genomic data obtained during the last decade. The aim was to develop a user-friendly ...
The p160 ER co-regulators predi ...
The SRC family of ER co-regulators are frequently overexpressed in breast cancer. Overexpression of AIB1 appears to be linked to hormone resistance ...
Behavioral risk factors and the ...
Hispanics are more likely to be diagnosed with breast cancer at a younger age, with more advanced stage at diagnosis, hormone receptor-negative tumo ...
Cancer predisposing BARD1 mutat ...
The breast cancer susceptibility gene BARD1 (BRCA1-associated RING domain protein, MIM# 601593) acts with BRCA1 in DNA double-strand break (DSB) re ...
Addition of a histone deacetyla ...
Modulation of estrogen signaling is one of the most successful modalities for the treatment of estrogen receptor (ER)-positive breast cancer, yet de ...
P53 genotype as a determinant o ...
Clinical studies show that estrogen receptor-a (ER) expressing tumors tend to have better prognosis, respond to antiestrogen therapy and have wild-t ...
A long AAAG repeat allele in th ...
We sequenced the 50 UTR of the estrogenrelated receptor gamma gene (ERR-c) in *500 patient and volunteer samples and found that longer alleles of th ...
Breast cancer risk among women ...
Breast cancer is the leading cause of death among women worldwide. Studies in industrialised countries identified age at menarche, age at first full ...
Lack of efficacy to systemic ch ...
Metaplastic carcinoma of the breast (MCB) is a rare subtype of breast cancer. Anecdotal reports are available regarding its response to systemic che ...
Frondoside A inhibits breast ca ...
Frondoside A, derived from the sea cucumber Cucumaria frondosa has demonstrable anticancer activity in several models, however, the ability of Frond ...
Correlation of breast cancer su ...
To understand the biology of low-risk breast cancer alleles, and to investigate whether these loci also contribute to disease progression that was o ...
Co-amplification of the HER2 ge ...
Co-amplification of the centromere on chromosome 17 (CEP17) and HER2 can occur in breast cancer. Such aberrant patterns (clusters) on CEP17 can be m ...
Physical activity and breast ca ...
The study was conducted to determine the effect of physical activity on DNA methylation and to predict the consequence of this effect concerning gen ...
The impact of obesity on receip ...
Disparities in the receipt of adjuvant chemotherapy for early stage breast cancer is an important factor influencing mortality. We investigated whet ...
The earwax-associated SNP c.538 ...
Genetic polymorphisms of human ABC-transporter genes have been suggested to modulate breast cancer risk in the general population. In particular ABC ...
Breast cancer risk assessment i ...
Although the benefit of screening mammography for women over 69 has not been established, it is generally agreed that screening recommendations for ...
Mesenchymal stem cells from pri ...
Mesenchymal stem cells (MSCs) play a critical role in promoting cancer progression. However, it is not clear whether MSCs are located in breast canc ...
Genotypes and phenotypes of IGF ...
The relationship between IGF genotypes and phenotypes in breast tumors and their associations with breast cancer risk remain to be elucidated. Such ...
Patient and tumor characteristi ...
Few data are available on bilateral breast cancer in the screening population. The aim of this study was to determine patient and tumor characterist ...
Genetic variation in proinflamm ...
Proinflammatory cytokines are associated with age-related diseases including arthritis and heart disease. IL6 and TNF also play key roles in estroge ...
Specific kinesin expression pro ...
Breast cancer is a genetically heterogenous disease with subtypes differing in prognosis and chemosensitivity. The basal-like breast cancer (BLBC) m ...
Inhibitors of histone demethyla ...
Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene expression in breast can ...
Protective effect of longstandi ...
Reproductive risk factors and associated risk for breast cancer have been and remain the subject of intense investigation. Particular attention is g ...
Immunohistochemically defined s ...
The aim of this study is to evaluate the outcome of occult breast cancer (OBC) in patients with axillary presentation overall and according to the i ...