Inhibition of Protein Kinase c-Src as a Therapeutic App ...
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Inhibition of Protein Kinase c- ...
c-Src is a proto-oncogene involved in the genesis of and invasion by many cancers. This non-receptor tyrosine kinase also plays a crucial role in bon ...
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Towards Retinoid Therapy for Al ...
Alzheimer’s disease(AD) is associated with a variety of pathophysiological features, including amyloid plaques, inflammation, immunological changes, ...
302.17 KB
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Epigenetic Control of MicroRNA ...
MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either ...
349.54 KB
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Coordination of Ribosomal Prote ...
Cells grow in response to nutrients or growth factors, whose presence is detected and communicated by elaborate signaling pathways. Protein kinases p ...
150.85 KB
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Abnormal Choline Phospholipid M ...
Elevated contents of choline phospholipid metabolites are typically detected by nuclear magnetic resonance spectroscopy (MRS) in human and animal tum ...
586.82 KB
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Negative Regulation of TCR Sign ...
To prevent the occurrence and expansion of autoreactive T cell clones, and hence the development of autoimmune disease (such as multiple sclerosis, r ...
دانلود 1
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Myostimulating Effect of the Aq ...
The effects of the aqueous extract of Khaya senegalenis (Desr) A. Juss. (Meliaceae) (EAKS) were evaluated on the contractile activity of the guinea-p ...
205.28 KB
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A Disposable Electrochemical Gl ...
We report here the development of a novel disposable-type glucose enzyme sensor based on a screen-printed carbon electrode (SPCE) employing a catalyt ...
785.59 KB
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A Micro-fluidic System for the ...
We present a new technique for the evaluation of polymer blood compatibility that makes use of a microchannel array flow analyzer and we describe and ...
2.02 MB
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New Emergent Nanotechnologies i ...
In this review we explore the advantages deriving from the use of either enzymes or binding proteins to develop non-consuming substrate fluorescence ...
452.78 KB
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Gene Therapy Targeting Nuclear ...
Nuclear factor (NF)-..B is regarded as one of the most important transcription factors and plays an essential role in the transcriptional activation ...
267.77 KB
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Functional Characterization of ...
Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed ..-(1-4)- linked D-glucosamine (deacetylated un ...
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Folding, Assembly, and Stabilit ...
Heme cofactors of transmembrane cytochromes are crucial for mediating charge transfer across membranes during aerobic and anaerobic electron transpor ...
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The Initiation Mechanisms of Ge ...
Experiments with a cell culture of ascitic hepatoma A/He showed that dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) in a co ...
254.41 KB
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Advances in Allergen-Specific I ...
After several decades of controversies, allergen specific immunotherapy (SIT) was recognized as an effective treatment for respiratory and hymenopter ...
220.72 KB
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Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
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Colloidal and Pharmacological A ...
Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...
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Role of ARBs in the Blood Hyper ...
Hypertension has a worldwide high incidence in the general population and undoubtedly it is the most important risk factor for cardiovascular morbidi ...
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Targeted Elimination of Leukemi ...
Despite recent advances, treatment of leukemia is often not curative. New insights indicate that this may be attributable to a small population of th ...
480.64 KB
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Japanese Encephalitis: Epidemio ...
Japanese encephalitis is a major cause of encephalitis in Asia. An estimated 50 000 cases occur in largely rural areas of the south and east Asian re ...
1.81 MB
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Genomic characterization of the ...
Background: Mitochondrial tumor suppressor gene 1 (MTUS1) has been recently identified as a candidate tumor suppressor gene which resides in a genomi ...
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Cross genome comparisons of ser ...
Background: Serine proteases are one of the largest groups of proteolytic enzymes found across all kingdoms of life and are associated with several e ...
713.61 KB
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Nuclear anomalies in exfoliated ...
Petroleum derivative consist of a complex mixture of chemical compounds. Petrol station workers who pump fuel to vehicles absorb the products of fuel ...
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Complement receptor 1 gene poly ...
Complement receptor 1 (CR1) is a membrane protein mediating the transport of immune complexes (ICs) to phagocytes, and at least two polymorphisms on ...
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Expression of an antibody-targe ...
A recombinant gene coding for an antibody-targeted urokinase-type plasminogen activator was constructed for the purpose of enhancing the thrombolytic ...
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