GMP production of [18F]FDOPA an ...
Introduction Lately, 6-[18F]fluoro-L-DOPA (FDOPA) has found increase in its clinical demand for whole-body positron emission tomography (PET) scans, ...
Predictors of abnormal heart ra ...
Objective To identify predictors of abnormal HR response to dipyridamole (DIP) in patients undergoing myocardial perfusion SPECT (MPS). Background ...
Diagnostic role of initial rena ...
Objective Assessment of the first febrile urinary tract infection (UTI) in children has been the subject of debate for many years. Diagnosis of acut ...
Comparison of left ventricular ...
Objective ECG-gated myocardial perfusion scintigraphy (MPS) can be used to determine several cardiac functional parameters (e.g., left ventricular e ...
The DSM IV diagnoses of melanch ...
Atypical and melancholic subtypes of depression based on the Diagnostic and Statistical Manual (DSM) IV are important concepts, especially for biolo ...
Hematopoietic cytokines for car ...
influence cellular proliferation, differentiation, maturation, and lineage commitment in the bone marrow, include granulocyte colony-stimulating fac ...
Glycogen synthase kinase 3 beta ...
The role of glycogen synthase kinase 3 beta (GSK-3b) in modulating Notch control of vascular smooth muscle cell (vSMC) growth (proliferation and apo ...
Diastolic dysfunction and arrhy ...
Transgenic (TG) Ca2?/calmodulin-dependent protein kinase II (CaMKII) dC mice develop systolic heart failure (HF). CaMKII regulates intracellular Ca2 ...
Distinct mechanisms for diastol ...
Chronic pressure-overload and diabetes mellitus are two frequent disorders affecting the heart. We aimed to characterize myocardial structural and f ...
Electromechanical effects of th ...
Activation of the atrial renin–angiotensin system plays an important role in the pathophysiology of atrial fibrillation (AF). The pulmonary vein (PV ...
Genetic profile of astrocytic a ...
Low-grade diffuse gliomasWHOgrade II (diffuse astrocytoma, oligoastrocytoma, oligodendroglioma) are characterized by frequent IDH1/2 mutations ([80% ...
Brain metastases exhibit gross ...
Candidate genes involved in metastasis to the brain require investigation. In the present study, the adenomatous polyposis coli (APC) gene was analy ...
Expression of stem cell marker ...
Glioblastoma is dependent on a specific signaling pathway to maintain its tumor phenotype. The receptor tyrosine kinase (RTK) family mediates the mu ...
Diffuse large B-cell lymphoma w ...
Cavernous angiomas or hemangiomas and malignant lymphomas rarely involve the cavernous sinus. We report the case of a 72-year-old man with right cir ...
Amplification of ESR1 may predi ...
The estrogen receptor (ER) is the target of tamoxifen, but endocrine therapies do not benefit all patients with ER positive tumors. We therefore hyp ...
Functional implication of TRAIL ...
Recently, TRAIL function has been elucidated beyond its known classical role of mediating cellular homeostasis and immune surveillance against trans ...
Enhanced serine production by b ...
Since bone metastatic breast cancer is an incurable disease, causing significant morbidity and mortality, an understanding of the underlying molecul ...
One size does not fit all: qual ...
Adjuvant endocrine therapy for breast cancer is associated with significant improvements in disease-related outcomes. Five years of tamoxifen therap ...
Effects of toremifene and anast ...
The potential long-term adverse effects on quality of life have to be considered when selecting agents for adjuvant hormonal treatment for postmenop ...
Effects on survival of menstrua ...
Adjuvant surgical oophorectomy is an effective and remarkably cost effective treatment for premenopausal women with hormone receptor positive operab ...
Chemotherapy for metastatic bre ...
Although new chemotherapeutic drugs for metastatic breast cancer (MBC) have been approved over the past decade, it is unclear whether this has chang ...
Unfavourable pattern of metasta ...
Little is known about time trends in metastases in the patients treated in routine health care facilities without metastases at diagnosis (M0) and a ...
Risk of contralateral breast ca ...
Rare deleterious mutations in BRCA1 and BRCA2 are associated with an elevated risk of breast and ovarian cancer. Whether or not common variants in t ...
Reversed urban–rural difference ...
The purpose of this study was to examine the urban–rural difference in breast cancer mortality between 2002 and 2008 in China. A longitudinal analys ...
Unmet supportive care needs: a ...
The comparison of psychosocial needs across different cultural settings can identify cultural and service impacts on psychosocial outcomes. We compa ...