Phosphorylated S6K1 is a possible marker for endocrine ...
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Phosphorylated S6K1 is a possib ...
Cross-talk between the estrogen receptor and the mammalian target of rapamycin (mTOR) pathway is one of the mechanisms of endocrine therapy resistan ...
371.86 KB
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Declining melatonin levels and ...
Serum melatonin (MLT) levels have been reported to diminish significantly by the 5th and 6th decades of life as the incidence of breast cancer incre ...
388.37 KB
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Glycodelin expression associate ...
Glycodelin (encoded by PAEP gene) is a secreted lipocalin protein mainly expressed in reproductive tissues, but also in several tumour types. In the ...
254.00 KB
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Genomics, histopathology, and t ...
Efforts to improve recurrence risk stratification for breast cancer patients have increasingly focused on rapidly developing gene expression profili ...
87.46 KB
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Image-guided tumor resection us ...
Tumor involvement of resection margins is found in a large proportion of patients who undergo breastconserving surgery. Near-infrared (NIR) fluoresc ...
666.95 KB
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Enhanced serine production by b ...
Since bone metastatic breast cancer is an incurable disease, causing significant morbidity and mortality, an understanding of the underlying molecul ...
500.10 KB
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Clinicopathologic and molecular ...
Akt/PKB serine/threonine kinase is a leading signalling modulator for several cellular processes including metabolism, growth, proliferation and sur ...
375.75 KB
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Distinct function of androgen r ...
Steroid receptor coactivators are important in regulating the function of the receptors in endocrine organ development and in cancers, including bre ...
1.70 MB
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Insulin like growth factor bind ...
Previously, we have shown that insulin-like growth factor binding protein-7 (IGFBP-7) expression is inversely correlated with disease progression in ...
750.15 KB
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Targeting trastuzumab-resistant ...
Targeting HER-2 over-expressing breast cancer cells with trastuzumab has resulted in significant improvements in both disease-free and overall survi ...
573.27 KB
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Does radiotherapy planning with ...
This prospective study investigated radiation dose and volume changes during breathing cycle. Ten patients with left breast carcinoma receiving radi ...
630.54 KB
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Identification of immunodominan ...
Mammaglobin-A (MGBA), a 10-kD protein, is over expressed in 80% of primary and metastatic human breast cancers. Breast cancer patients demonstrate h ...
425.81 KB
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Prevalence of the variant allel ...
Recently, a variant allele in the 30UTR of the KRAS gene (rs61764370 T[G) was shown to be associated with an increased risk for developing non-small ...
203.35 KB
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Tumor–stroma ratio in the prima ...
Stroma tissue surrounding cancer cells plays an important role in tumor development and behavior. In colorectal cancer, it has been found that the a ...
413.27 KB
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International distribution and ...
The c.156_157insAlu BRCA2 mutation has so far only been reported in hereditary breast/ovarian cancer (HBOC) families of Portuguese origin. Since thi ...
332.17 KB
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The rexinoid bexarotene repress ...
Bexarotene is an RXR-selective vitamin A analog that has been shown to prevent ER-negative mammary tumorigenesis in animal models. While investigati ...
دانلود 2
631.63 KB
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Targeting mutant p53 protein an ...
Breast cancer progression depends upon the elaboration of a vasculature sufficient for the nourishment of the developing tumor. Breast tumor cells f ...
1.07 MB
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Three-dimensional collagen repr ...
The behavior of breast epithelial cells is influenced by their microenvironment which includes stromal cells and extracellular matrix (ECM). During ...
566.25 KB
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Oral fluoropyrimidine may augme ...
The present preclinical study was designed to evaluate a new combination therapy comprised of the aromatase inhibitor anastrozole (ANA) and the oral ...
526.71 KB
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RAD51 135G>C does not modify ...
A single-nucleotide polymorphism (SNP) in the 50-untranslated region (UTR) of RAD51, 135G[C (rs1801320), was reported to be associated with an incre ...
288.97 KB
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Nicotine-induced human breast c ...
Previous studies have demonstrated that the persistent exposure of human bronchial epithelial cells to nicotine (Nic) through nicotinic acetylcholin ...
795.89 KB
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Interactions between breast can ...
The preferential metastasis of breast cancer cells to bone is a complex set of events including homing and preferential growth which may include uni ...
643.92 KB
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Let-7 family miRNAs regulate es ...
In order to understand how microRNAs (miRNAs) regulate breast cancer tumorigenesis, a miRNA expression microarray screening was performed using RNA ...
815.83 KB
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Combined Src and ER blockade im ...
Antiestrogen therapies arrest susceptible estrogen receptor (ER)-positive breast cancers by increasing p27. Since Src phosphorylates p27 to promote ...
573.30 KB
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COX2 expression in prognosis an ...
In breast cancer, the prognostic impact of COX2 expression varies widely between studies. We examined the prognostic value of COX2 expression in a ...
519.55 KB
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