Burkitt Lymphoma and Atypical B ...
Burkitt lymphoma (BL) is a mature B-cell non- Hodgkin lymphoma with an aggressive clinical course. Since the advent of short, intensive, multiagent ...
The Role of Transplantation in ...
Rituximab has improved the prognosis of patients with diffuse large B-cell lymphoma, but a high proportion of patients with advanced disease will re ...
New Immunomodulatory Drugs in M ...
Multiple myeloma (MM) is an incurable malignancy of plasma cells. The introduction of thalidomide was a milestone in the treatment of MM. Thalidomid ...
Special Issues in Myeloprolifer ...
Special issues in myeloproliferative neoplasms (MPN) comprise clinical conditions with high relevance for the duration and quality of the patient’s ...
Future Therapies for the Myelop ...
Ever since their description as “myeloproliferative syndromes” by William Dameshek in 1951, the myeloproliferative neoplasms (MPNs) have been manage ...
The Search for Better Prognosti ...
Myelodysplastic syndromes (MDS) are a group of heterogeneous bone marrow disorders characterized by a failure of hematopoiesis and an increased prop ...
Therapeutic Modalities for Pati ...
The treatment of myelodysplastic syndromes (MDS) involves a complex algorithm that depends on multiple factors, including symptoms, performance stat ...
Recognition and Management of S ...
It is increasingly recognized that sleep-disordered breathing (SDB) is a common modifiable risk factor for cardiovascular disease with significant i ...
Controversies in Cardiac Resync ...
Cardiac resynchronization therapy (CRT) is well established in the treatment of patients with heart failure, but lacks data addressing sex differenc ...
Mechanical Bridge to Decision: ...
While great strides have been made in the management of heart failure syndromes, acute refractory cardiogenic shock carries a dismal prognosis. Init ...
Targeting Hyponatremia and Hemo ...
Current treatment of acute decompensated heart failure (ADHF) has not reduced the significant morbidity or mortality associated with this disease, a ...
Novel Natriuretic Peptides: New ...
The natriuretic peptides (NPs) are a group of structurally similar yet genetically distinct peptides that have diverse actions in cardiovascular, re ...
Intravenous Iron in Heart Failu ...
Iron deficiency is commonly seen in congestive heart failure (CHF) in both anemic and nonanemic patients. In six studies in which these iron-deficie ...
A Clinical Perspective on Gastr ...
The incidence of gastric neuroendocrine tumors (NETs) has increased exponentially based on widespread use of endoscopy and a greater pathological a ...
Prevention and Treatment of Pos ...
Poorly controlled Crohn’s disease (CD) often requires surgery for such complications as strictures, fistulas, and abscesses. The goal of postoperati ...
Quality of Care in Inflammatory ...
Advances in the treatment of inflammatory bowel disease (IBD) are published routinely in medical journals. Some treatments are sufficiently helpful ...
Big Changes Are Coming in Hepat ...
The story of hepatitis C virus (HCV) therapy is about to add one of its biggest chapters. From the serendipitous beginnings in the 1980s when invest ...
Idiosyncratic Drug-Induced Live ...
Drug-induced liver injury (DILI) is a rare but potentially devastating adverse drug reaction. Its presentation can range from asymptomatic elevation ...
Advances in Alcoholic Liver Dis ...
Alcoholic liver disease (ALD) remains a leading cause of death from liver disease in the United States. In studies from the Veterans Administration, ...
Modern Approach to Hepatocellul ...
Hepatocellular carcinoma (HCC) used to be considered a universally fatal disease. Today, however, we have tools to identify patients at risk for HCC ...
Bone Disorders in Chronic Liver ...
Bone disease is a major complication of chronic liver disease. Osteomalacia is quite uncommon despite low vitamin D levels in the majority of patien ...
Pulmonary Complications of Cirr ...
Pulmonary vascular complications of liver disease comprise two distinct clinical entities: hepatopulmonary syndrome (HPS—microvascular dilatation an ...
Advances in the Evaluation and ...
Minimal hepatic encephalopathy (MHE) is a neurocognitive disorder that affects up to 80% of cirrhotic patients. Similar to overt hepatic encephalopa ...
Management of Refractory Ascite ...
One of the most common manifestations of the development of portal hypertension in the patient with cirrhosis is the appearance of ascites. Once asc ...
Update on the Role of Endoscopi ...
Chronic pancreatitis (CP) remains an important healthcare problem that adversely affects quality of life. Endoscopic ultrasound (EUS) is a preferred ...