High-performance tangeptial flo ...
High-performance tangential flow filtration (HPTFF) is a new technology for protein and nucleotide purification. Conventional ultrafiltration (UF) is ...
State of the art in the deliver ...
In photodynamic therapy, one of the problems limiting the use of many photosensitizers (PS) is the difficulty in preparing pharmaceutical formulation ...
High-cell-density cultivation o ...
High-cell-density cultivation (HCDC) is re- quired to improve microbial biomass and product for- mation substantially. An overview of HCDC is given ...
Infuence of acetic acid on the ...
High-cell-density cultivations of Escherichia coli K12 in a dialysis reactor with controlled levels of dissolved oxygen were carried out with di€ere ...
Novel Escherichia coli Strain A ...
An important characteristic of promoters used in recombinant protein production in Escherichi coli is their inducibility in a simple and cost-effect ...
Modelling nutrient transport in ...
Recent experimental studies suggest that hollow fibre membrane bioreactors (HFMBs) may be used to grow three-dimensional (3D) bone tissue, which may ...
Interior-point methods for redu ...
Typical chemical process optimization problems have a large number of equations, but relatively few degrees of freedom. A reduced Hessian successive ...
Selection of Highly Productive ...
In mammalian cell culture, the selection of high producers is a critical step in efficient recombinant protein production. Drug-resistance selection ...
A theoretical and experimental ...
The behavior of membrane bioreactors operating in recycle configuration is characterized from both a theoretical and an experimental point of view. T ...
Reducing the Glucose Uptake Rat ...
Although glucose is an inexpensive substrate widely used as a carbon source in Escherichia coli recombinant fermentation technology, 10–30% of the ...
Reduction of Aerobic Acetate Pr ...
Acetate excretion by Escherichia coli during aerobic growth on glucose is a major obstacle to enhanced recombinant protein production. We report here ...
Milk protein interfacial layers ...
The properties of milk protein-stabilised, oil-in-water emulsions are determined by the structure and surface rheology of the adsorbed layer at the o ...
PEO-brush at the liquid:gas int ...
Water-soluble amphiphilic polyethylene oxide-polypropylene oxide-polyethylene oxide (PEO-PPO-PEO) triblock copolymers (pluronics and synperonics) are ...
Structure of grafted polymers, ...
Neutron re#ectometry is used to investigate the structure of polymers end-grafted to an interface at high grafting densities, so-called brushes. Our ...
Imatinib plus Granulocyte Colon ...
Background: The BCR/ABL tyrosine kinase inhibitor imatinib is highly effective in the treatment of chronic myeloid leukemia (CML) but fails to elimin ...
Conformational transitions of a ...
We report here the first extensive study of the conformational transitions of a diblock polyampholyte made of two symmetric blocks, one positively, ...
Asymmetric Multiblock Copolymer ...
at the air–water interface. Each block is made of a sequence A of ZA hydrophobic and of a sequence B of ZB hydrophilic monomers. The A and B sequenc ...
A New Methodology for Studying ...
new methodology has been developed for studying the adsorption behavior of proteins at oil–water interfaces. This technique employs the radiotracer ...
B-Casein Bilayer Adsorption at ...
Ellipsometric and surface pressure studies of â-casein adsorption layers at the water/air interface support the idea of a model that assumes the for ...
Effect of Ethanol on the Struct ...
The adsorption of b-casein at the air–solution interface has been monitored in equilibrium conditions by neutron reflectivity. It was observed that ...
Surface pressure of protein ads ...
In the study of protein adsorption at fluid interfaces, the relation between the surface concentration and the surface pressure is of general interes ...
High-cell-density cultivation o ...
High-cell-density cultivation (HCDC) is re- quired to improve microbial biomass and product for- mation substantially. An overview of HCDC is given ...
Roles and Applications of Small ...
Proteome profiling of the inclusion body (IB) fraction of recombinant proteins produced in Escherichia coli suggested that two small heat shock prot ...
Multiple Myeloma Emerging after ...
The coexistence of lung cancer and multiple myeloma (MM) is rare. A search of the English literature revealed only 5 case reports to date. We describ ...
Studies Related to the Scale-Up ...
Multiparameter flow cytometric techniques developed in our laboratories have been used for the “atline” study of fed-batch bacterial fermentations. ...