Genetics of Interleukin 1 Receptor-Like 1 in Immune and ...
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Getting a Grip on Complexes
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Genetics of Interleukin 1 Recep ...
Interleukin 1 receptor-like 1 (IL1RL1) is gaining in recognition due to its involvement in immune/inflammatory disorders. Well-designed animal studie ...
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Maps of cis-Regulatory Nodes in ...
The availability of complete human and other metazoan genome sequences has greatly facilitated positioning and analysis of various genomic functional ...
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Therapeutics Based on microRNA: ...
Hepatocellular carcinoma (HCC) is a serious public health hazard. Polygenes involvement, accumulation of genetic and epigenetic changes and immune re ...
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Validation of Inference Procedu ...
The availability of high-throughput genomic data has motivated the development of numerous algorithms to infer gene regulatory networks. The validity ...
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HLA Genes in Mayos Population f ...
HLA class I and class II alleles have been studied in 60 unrelated people belonging to Mayos ethnic group, which lives in the Mexican Pacific Sinaloa ...
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Investigation of Molecular Mech ...
Recent advances into the understanding of molecular mechanism of chronic pain have been largely developed through the use of genetic manipulations. T ...
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Genome Annotation in Plants and ...
In this era of whole genome sequencing, reliable genome annotations (identification of functional regions) are the cornerstones for many subsequent a ...
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DNA Instability at Chromosomal ...
Human chromosomal fragile sites are specific genomic regions which exhibit gaps or breaks on metaphase chromosomes following conditions of partial re ...
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Discovering Tumor Suppressor Ge ...
Classical tumor suppressor gene discovery has largely involved linkage analysis and loss-of-heterozygosity (LOH) screens, followed by detailed mappin ...
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The Basic Biology of BACE1: A K ...
Alzheimer’s disease (AD) is an intractable, neurodegenerative disease that appears to be brought about by both genetic and non-genetic factors. The n ...
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
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High-Throughput Genomics Enhanc ...
Tomato (Solanum lycopersicum) is considered a model plant species for a group of economically important crops, such as potato, pepper, eggplant, sinc ...
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The GNAS Locus: Quintessential ...
The currently estimated number of genes in the human genome is much smaller than previously predicted. As an explanation for this disparity, most ind ...
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Functional Genomics of Brain Ag ...
Pivotal brain functions, such as neurotransmission, cognition, and memory, decline with advancing age and, especially, in neurodegenerative condition ...
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Perspectives in Cell Cycle Regu ...
The ability of an animal, normally dependent on aerobic respiration, to suspend breathing and enter an anoxic state for long term survival is clearly ...
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Composition and Functions of th ...
Fusion of the influenza virus envelope with the endosomal membrane of host cells is mediated by the hemagglutinin glycoprotein (HA). The most conserv ...
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Crystal structure of SV40 large ...
The transformation potential of Simian Virus 40 depends on the activities of large T-antigen (LTag), which interacts with several cellular tumor supp ...
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Indispensable Roles of Plastids ...
The plastid is an organelle vital to all photosynthetic and some non-photosynthetic eukaryotes. In the model plant Arabidopsis thaliana, a number of ...
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Bacterial Stationary-State Muta ...
Mechanisms of cellular adaptation may have some commonalities across different organisms. Revealing these common mechanisms may provide insight in th ...
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Identification of Salmonella en ...
Salmonella enterica serovar Typhi is a human pathogenic microorganism with a very complex infective cycle, involving the transit of bacteria across d ...
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DNA Transposons: Nature and App ...
Repeated DNA makes up a large fraction of a typical mammalian genome, and some repetitive elements are able to move within the genome (transposons an ...
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Genetic Interference: Don’t Sta ...
Meiosis is a dynamic process during which chromosomes undergo condensation, pairing, crossing-over and disjunction. Stringent regulation of the distr ...
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Getting a Grip on Complexes
We are witnessing tremendous advances in our understanding of the organization of life. Complete genomes are being deciphered with ever increasing sp ...
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Genetic Mechanisms and Aberrant ...
Gastric adenocarcinoma occurs via a sequence of molecular events known as the Correa’s Cascade which often progresses over many years. Gastritis, typ ...
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Comparative Approach of the de ...
Over the second half of 20th century much research on lipogenesis has been conducted, especially focused on increasing the production efficiency and ...
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