Paraneoplastic polymyositis ass ...
The association of polymyositis and cancer was first described in 1916, the most frequent cancers being mammary and gynecological for women, broncho ...
EMSY and CCND1 amplification in ...
EMSY is a putative oncogene amplified in a minority of breast carcinomas, its protein product interacts with and transcriptionally silences BRCA2. W ...
Genetic variants in ultraconser ...
Ultraconserved elements (UCEs) are the most extreme representatives of conserved non-coding sequences. Recent studies have indicated thatUCEs are no ...
Replication of genome-wide disc ...
Genome-wide association studies (GWAS) have identified associations with robust statistical support for influencing breast cancer susceptibility. Mo ...
High estrogen receptor expressi ...
One of the most controversial questions in early breast cancer treatment is the need of chemotherapy in patients with estrogen receptor positive dis ...
Poly(ADP-ribose) polymerase-1 m ...
Although poly(ADP-ribose) polymerase-1 (PARP1) inhibition is a recent promising therapy in breast cancer, PARP1 expression in this disease is not kn ...
Agonists and antagonists of GnR ...
Metastasis to bone is a frequent problem of advanced breast cancer. Particularly breast cancers, which do not express estrogen and progesterone rece ...
Gene expression profiling assig ...
CHEK2 1100delC is a moderate-risk cancer susceptibility allele that confers a high breast cancer risk in a polygenic setting. Gene expression profil ...
A HRM-based screening method de ...
The RAD51C gene has been recently proposed as a high-penetrance breast and ovarian cancer gene. However, early replication studies have failed to co ...
Lack of association between hOG ...
Recently, we read with great interest the article ‘‘The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis’’ published online in A ...
Metabotropic glutamate receptor ...
Metabotropic glutamate receptors are G-protein- coupled receptors normally expressed in the central nervous system where they mediate neuronal excit ...
Association between polymorphis ...
The renin–angiotensin system (RAS) has been considered to be implicated in the development of breast cancer. However, the results are inconsistent. ...
Gene expression profile testing ...
As gene expression profile (GEP) testing for breast cancer may provide additional prognostic information to guide the use of adjuvant chemotherapy, ...
A prognostic model for lymph no ...
model for a more precise prognosis of the risk of relapse is needed to avoid overtreatment of lymph node-negative breast cancer patients. A large de ...
Enhancement of chemotherapeutic ...
A subset of primary breast cancers and breast cancer cell lines express a hypermethylation defect (characterized by DNMT hyperactivity and DNMT3b ov ...
IL-15 and IL-2 increase Cetuxim ...
Triple negative breast cancer (TNBC) patients are not likely to benefit from anti-estrogen or anti-HER2 therapy and this phenotype is associated wit ...
Correlation between docetaxel-i ...
Steroids and H2 blockers are commonly used as supportive care for taxane-containing chemotherapy, but they also affect docetaxel’s primary metaboliz ...
Insulin-like growth factor-1 re ...
Insulin-like growth factor-1 receptor (IGF1R) plays a key role in the initiation and progression of breast cancer. However, its prognostic relevance ...
Biopsy sampling of breast lesio ...
Needle biopsy is now the initial investigation of choice for the pre-operative diagnosis of breast lesions. This includes core needle biopsy (CNB) a ...
The prognostic significance of ...
Although the favourable role of T lymphocyte populations in different tumour types is established, that of B cells is still a matter of debate and n ...
Pilot study of radiofrequency a ...
Background There is increasing demand for minimally invasive treatments for small breast cancer mainly because of the desire for better cosmetic res ...
Primary pure signet cell carcin ...
Signet ring cell carcinoma (SRCC) of the breast is a rare tumor that is classified into mucinous carcinoma and other tumors with abundant mucin as a ...
Association between the 2402GA, ...
Background and Purpose Recent data have shown that the hemostatic system may play a role in cancer development and progression. To test whether fact ...
Background enhancement of mamma ...
Background Just as mammographic breast density influences mammographic sensitivity, the degree of background enhancement in breast magnetic resonanc ...
Risk Factors and Complications ...
Purpose This study was designed to investigate the risk factors and complications of difficult retrieval (DR) of embolic protection devices (EPDs) i ...