Regulation of kidney developmen ...
There is accumulating evidence that gene expression can be regulated independently of DNA sequence changes, also called epigenetic modifications. Hi ...
Hepatoblastoma and prune belly ...
Prune belly syndrome (PBS) is a congenital anomaly characterized by the clinical triad of lax abdominal musculature, bilateral cryptorchidism, and a ...
Cyclophosphamide in steroid-dep ...
In order to determine the long-term effects of cyclophosphamide (CPO) and to identify parameters associated with sustained remission, we retrospecti ...
Urinary levels of TGF â-1 and o ...
This study aimed to identify noninvasive biomarkers of clinically significant nephrouropathies in patients with antenatal renal and/or urinary tract ...
Bone assessment in children wit ...
Bone damage in children with chronic kidney disease (CKD) is a challenge for pediatric nephrologists. Areal measurements of bone mineral density (BM ...
Cyclosporin A therapy for Henoc ...
To evaluate the therapeutic role of cyclosporin A (CyA) for the treatment of Henoch–Schِnlein nephritis (HSN), 29 patients (18 boys, 11 girls) with ...
Additive effect of PPAR-م agoni ...
Our recent in vitro study demonstrated peroxisome proliferator-activated receptor-م (PPAR.م) agonist potentiated the anti-inflammatory effect of ang ...
A 25-year experience with pedia ...
Anti-glomerular basement membrane (anti-GBM) disease, which is extremely uncommon in children, is characterized by rapidly progressive glomeruloneph ...
Uncharted waters: nephrogenesis ...
The major functions of the vertebrate kidney are the removal of metabolic waste and the balance of salt and water. These roles are fulfilled by neph ...
Urinary MMP-9/NGAL complex in c ...
The matrix metalloproteinase-9 (MMP-9) and neutrophil gelatinase associated lipocalin (NGAL) are shown to increase in an inflammatory situation. Bas ...
Assessment of long-term renal c ...
We assessed the long-term renal complications in a regional cohort of extremely low birth weight (ELBW) children born in 2002–2004. The study group, ...
Henoch-Schِnlein purpura nephri ...
Nephritis develops in 18–81% of Henoch- Schِnlein purpura patients, and the long-term outcomes of this nephritis show great variation. A nephrotic s ...
Rituximab for refractory cases ...
Rituximab has been used over the last decade as a rescue therapy for refractory cases of nephrotic syndrome (NS). Here we report the use of rituxima ...
KIM-1 and NGAL: new markers of ...
Congenital obstructive nephropathy is the primary cause of chronic renal failure in children. Rapid diagnosis and initiation of the treatment are vi ...
Markers of childhood lupus neph ...
Current treatment regimens for childhood lupus nephritis (LN) are associated with significant side-effects and toxicity in vulnerable phases of grow ...
Antioxidant status of children ...
The production of free radicals can cause renal injury and play an important role in the pathogenesis of idiopathic nephrotic syndrome. Markers of r ...
Usefulness of skin immunofluore ...
Lupus nephritis (LN) may represent a diagnostic problem, particularly in pediatric patients that present with typical histological lesions but do no ...
Kidney repair and stem cells: a ...
Over the last decade, stem cells have been the topic of much debate and investigation for their regenerative potential in the case of renal injury. ...
Novel multidrug therapy for chi ...
An effective treatment for children with refractory nephrotic syndrome (NS), especially in those with cyclosporine (CsA)-resistant or CsA-intolerant ...
Clinical course and outcome of ...
We conducted a retrospective study on children with primary nephrotic syndrome (NS) to evaluate the clinical course and outcome of children with ste ...
Long-term follow-up after cyclo ...
Cyclophosphamide (CP) has been used for over 40 years in patients with steroid-sensitive nephrotic syndrome (SSNS) presenting frequent relapses or s ...
Liver fibrosis in recessive mul ...
Cystic renal diseases are characterized by intrarenal cysts of different size and number. Further important diagnostic criteria include, e.g., liver ...
Quality of life of pediatric pa ...
The interest in quality of life (QoL) studies has increased as they are useful instruments to evaluate and compare medical care delivery and the imp ...
Expression and function of the ...
Polyomavirus enhancer activator 3 (Pea3), belonging to the PEA3 subfamily of Ets transcription factors, is essential for certain organogenesis in ma ...
Novel mutations in steroid-resi ...
Steroid-resistant nephrotic syndrome (NS) remains one of the most intractable causes of end-stage renal disease in the first two decades of life. Se ...