ADHD and comorbid conduct problems among adolescents: a ...
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ADHD and comorbid conduct probl ...
Attention-deficit/hyperactivity disorder (ADHD) is a common child and adolescent disorder that is associated with negative outcomes (e.g., emotional ...
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232.54 KB
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Childhood obesity and parental ...
ADHD prevalence has risen in parallel with rising prevalence of pregnancy smoking and childhood obesity. The objective was to determine the epidemio ...
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187.94 KB
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A pilot study: differential eff ...
To examine the effects of methylphenidate- OROS (MPH-OROS) on working memory (WM) and attention functions in children with attention-deficit hypera ...
252.07 KB
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Comparison of SHR, WKY and Wist ...
Spontaneously hypertensive rats (SHR) and its counterpart, the Wistar-Kyoto rats (WKY), are probably the most often used animal model of ADHD. Howev ...
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New neuropathological findings ...
Unverricht–Lundborg disease (EPM1A), also known as Baltic myoclonus, is the most common form of progressive myoclonic epilepsy. It is inherited as a ...
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Four-repeat tauopathy clinicall ...
A man aged 55 with negative family history presented with progressive decline in spatial orientation and visual functions for 2 years. He showed imp ...
640.98 KB
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Superficial neurofibromas in th ...
First described in the past decade, schwannomatosis is a syndrome distinct from neurofibromatosis 2 (NF2). It is characterized by the development of ...
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Neuronal migration disorders in ...
Microcephalic osteodysplastic primordial dwarfism (MOPD) is a rare microlissencephaly syndrome, with at least two distinct phenotypic and genetic ty ...
1.22 MB
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PI3K/AKT pathway alterations ar ...
Pilocytic astrocytomas (PA) are well-differentiated gliomas having a favorable prognosis when compared with other diffuse or infiltrative astrocytom ...
1.18 MB
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Defects in amphiphysin 2 (BIN1) ...
Myotubular myopathy and centronuclear myopathies (CNM) are congenital myopathies characterized by generalized muscle weakness and mislocalization of ...
2.18 MB
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The application of in vitro cel ...
A key event in the pathogenesis of prion diseases is the conversion of the normal cellular isoform of the prion protein into the disease-associated ...
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Genome-wide comparison of pair ...
Array comparative genomic hybridization (aCGH) is a powerful tool for detecting DNA copy number alterations (CNA). Because diffuse malignant gliomas ...
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Mutation-specific IDH1 antibody ...
Isocitrate dehydrogenase 1 (IDH1) mutations are frequent in astrocytomas, oligoastrocytomas and oligodendrogliomas. We previously reported the gener ...
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1.19 MB
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Cellular and sub-cellular patho ...
The transmissible spongiform encephalopathies (TSEs) or prion diseases of animals are characterised by CNS spongiform change, gliosis and the accumu ...
1.51 MB
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Preponderance of sonic hedgehog ...
Medulloblastoma (MB) represents approximately 4% of adult brain tumours, and as such is a poorly studied disease. Although many adult MB are treated ...
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Molecular biology and pathology ...
Prion diseases are believed to propagate by the mechanism involving self-perpetuating conformational conversion of the normal form of the prion prot ...
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Risk genotypes at TMEM106B are ...
TMEM106B has recently been identified as a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic ...
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The spectrum and severity of FU ...
Neuronal intermediate filament inclusion disease (NIFID), a rare form of frontotemporal lobar degeneration (FTLD), is characterized neuropathologica ...
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Cytoplasmic accumulation of TDP ...
TDP-43, encoded by TARDBP, is a ubiquitously expressed, primarily nuclear protein. In recent years, TDP-43 has been identified as the major patholog ...
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Pathological correlates of fron ...
Frontotemporal lobar degeneration (FTLD) is generally recognised as a disorder with presenile onset (that is before 65 years of age) with only occas ...
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Distinct pathological subtypes ...
Most cases of frontotemporal lobar degeneration (FTLD) are characterized by abnormal intracellular accumulation of either tau or TDP-43 protein. How ...
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Modulation of lipid peroxidatio ...
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder. Oxidative damage has been associated with pathological neuronal loss ...
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1.13 MB
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APP involvement in retinogenesi ...
Very few studies have examined expression and function of amyloid precursor protein (APP) in the retina. We showed that APP mRNA and protein are ex ...
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Glutathione depletion and overp ...
Parkinson’s disease is a neurodegenerative disorder characterized by severe motor deficits mainly due to degeneration of dopaminergic neurons in the ...
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Genetic Creutzfeldt-Jakob disea ...
The E200K mutation is the most frequent prion protein gene (PRNP) mutation detected worldwide that is associated with Creutzfeldt-Jakob disease (CJD ...
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