Impact of cytokine gene polymorphisms on risk and treat ...
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Impact of cytokine gene polymor ...
Autoreactive cytotoxic T cells play a key role in the pathogenesis of aplastic anemia (AA) by myelosuppressive cytokines including interferon-gamma, ...
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Contribution of VKORC1 and CYP2 ...
Within the Asian populations, Indian patients had been reported to require higher warfarin dose compared with the Chinese and Malay patients, and th ...
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Additional erythrocytic and ret ...
Hereditary spherocytosis (HS) is characterised by weakened vertical linkages between the membrane skeleton and the red blood cell’s lipid bilayer, l ...
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Paroxysmal nocturnal hemoglobin ...
Flow cytometric analysis of GPI-anchored proteins (GPI-AP) is the gold standard for diagnosis of paroxysmal nocturnal hemoglobinuria (PNH). Due to ...
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Anti-annexin V IgG and IgM anti ...
Vaso-occlusive crisis (VOC) is a significant cause of morbidity and mortality in sickle cell anemia (SCA) patients; however, its mechanisms are poor ...
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Severe congenital neutropenia i ...
We have analysed a family with nine congenital neutropenia patients in four generations, several of which we have studied in a long-term follow-up o ...
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Sickle-cell disease and malaria ...
Sickle-cell disease (SCD) patients are at high risk of developing malaria which is a major contributor to morbidity andmortality in this disease. In ...
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CYP2B6 gene single nucleotide p ...
CYP2B6 is a highly variable and polymorphic cytochrome P450 enzyme which plays a vital role in the degradation of some endogenous metabolites, xenob ...
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Long-term follow-up of patients ...
Prior to introduction of imatinib mesylate, the median survival of chronic myeloid leukemia (CML) patients was approximately 60 months and the stand ...
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Danazol as first-line therapy f ...
Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) plus cyclosporine A (CsA) is the standard treatment for aplastic anemia (AA) patie ...
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Overexpression of the EZH2, RIN ...
Epigenetics refers to the study of clonally inherited changes in gene expression without accompanying genetic changes. Previous research on the epig ...
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Chronic nonspherocytic hemolyti ...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common hereditary enzymopathies worldwide. Mostly G6PD deficient cases are a ...
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In situ RHAMM protein expressio ...
Treatment options for patients with high-risk acute myeloid leukemia (AML) include high-dose chemotherapy regimens in combination with allogeneic he ...
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Polo-like kinase 2 (SNK/PLK2) i ...
Polo-like kinase 2 (SNK/PLK2), a transcriptional target for wild-type p53 and is hypermethylated in a high percentage of multiple myeloma and B cell ...
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High prevalence of hepatitis B ...
We performed a large case–control study (3,932 cases, 15,562 controls) to investigate the association of hepatitis B virus (HBV) and hepatitis C vir ...
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Prevalence of H63D, S65C, and C ...
Hereditary HFE Hemochromatosis is an inherited disorder of iron metabolism that results from mutations in the HFE gene. Almost all patients with her ...
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Long-term outcome of hemizygous ...
The transcriptional regulator GATA1 is crucially involved in megakaryocytopoiesis and erythropoiesis. Mutations of the gene which is located on the ...
دانلود 1
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CLIPI: a new prognostic index f ...
Indolent primary cutaneous B cell lymphomas (PCBCL) generally have a good prognosis, but they often relapse leading in some cases to extracutaneous ...
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Long-term follow-up of clonal e ...
To assess the incidence rates and risk factors for clonal evolutions in aplastic anemia (AA) patients, we studied 802 hospitalization cases from Jan ...
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Iron status and treatment modal ...
Transfusion dependency and iron overload are common among patients with myelodysplastic syndromes (MDS) treated with red blood cell (RBC) transfusio ...
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Alkylating chemotherapeutic age ...
The adverse effects of melphalan and cyclophosphamide on hematopoietic stem cells are well-known; however, the effects on the mesenchymal stem cells ...
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Intrathecal application of dono ...
Extramedullary relapses after allogeneic stem cell transplantation, especially within the central nervous system (CNS), are not only difficult to tr ...
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Elevated frequencies of leukemi ...
Some 30% of acute myeloid leukemia (AML) patients display an internal tandem duplication (ITD) mutation in the FMS-like tyrosine kinase 3 (FLT3) gen ...
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The role of routine imaging pro ...
Despite improved initial therapies, a subgroup of patients with aggressive non-Hodgkin (A-NHL) and Hodgkin lymphomas (HL) will relapse after first r ...
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Expression of myelopoiesis-asso ...
The microRNA/miR deregulation in BCR-ABLnegative myelodysplastic-myeloproliferative neoplasms (MDS/MPN) is not known. Myelopoiesis-associated miR-1 ...
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