Outcome of triple-negative breast cancer in patients wi ...
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Outcome of triple-negative brea ...
More than 75% of breast cancers that develop in BRCA1 mutation carriers are triple-negative breast cancers (TNBC). The aim of this study was to comp ...
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Targeted and intracellular trig ...
Limiting tumor invasion to the surrounding healthy tissues has proven to be clinically relevant for anticancer treatment options. We have demonstrat ...
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Reproductive factors and histol ...
Evidence suggests that certain reproductive factors are more strongly associated with the incidence of lobular than of ductal breast cancer. The mec ...
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Serum CD44 levels and overall s ...
CD44 is an adhesion molecule involved in tumor cell invasion and metastasis. The function of CD44 in breast cancer is not understood completely, or ...
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NQO1 expression correlates inve ...
NQO1 participates in cellular defense against oxidative stress and regulates apoptosis via p53- and NFjB-mediated pathways. We have previously found ...
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Detection of circulating tumor ...
We read with great interest a recent article entitled ‘‘The prognostic role of circulating tumor cells (CTCs) detected by RT-PCR in breast cancer: a ...
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Mortality following bone metast ...
The aim of the study is to quantify the impact of bone metastasis and skeletal-related events (SREs) on mortality in older breast cancer patients. U ...
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Responsiveness of adjacent duct ...
Adjacent ductal carcinoma in situ (DCIS) is found in approximately 45%of invasive ductal carcinomas (IDC) of the breast. Pure DCIS overexpresses HER ...
دانلود 2
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A diagnostic gene profile for m ...
Classification of breast cancer into molecular subtypes maybe important for the proper selection of therapy, as tumors with seemingly similar histop ...
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MiR-28 regulates Nrf2 expressio ...
NF-E2-related factor 2 (Nrf2) is an important transcription factor involved in antioxidant response. Nrf2 binds antioxidant response elements (ARE) ...
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Gene expression profiling assig ...
CHEK2 1100delC is a moderate-risk cancer susceptibility allele that confers a high breast cancer risk in a polygenic setting. Gene expression profil ...
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Does the effect of weight lifti ...
The lymphedema diagnostic method used in descriptive or intervention studies may influence results found. The purposes of this work were to compare ...
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Associations of objectively ass ...
Physical activity reduces the risk of postmenopausal breast cancer through multiple inter-related biologic mechanisms; sedentary time may contribute ...
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A HRM-based screening method de ...
The RAD51C gene has been recently proposed as a high-penetrance breast and ovarian cancer gene. However, early replication studies have failed to co ...
دانلود 1
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Genomic profiling of mitochondr ...
Oncocytic carcinomas are composed of mitochondrion- rich cells. Though recognised by the WHO classification as a histological special type of breast ...
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Can we avoid axillary dissectio ...
There is considerable interest in foregoing axillary dissection (AD) when the sentinel node (SN) is positive in early breast cancer, particularly wh ...
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Lack of any association between ...
Active metabolites of tamoxifen are formed mainly by the action of cytochrome P450 2D6 (CYP2D6). Since there are controversies regarding association ...
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Routine pathologic parameters c ...
OncotypeDXTM is an RT-PCR-based assay used to predict chemotherapy benefit in patients with estrogen receptor (ER) positive breast cancers. We were ...
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Association of the germline TP5 ...
The tumor suppressor gene TP53 and its regulator MDM2 are both important players in the DNA-damage repair ‘‘TP53 response pathway’’. Common germline ...
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In situ detection of HER2:HER2 ...
HER2 overexpression/amplification is linked with poor prognosis in early breast cancer. Co-expression of HER2 and HER3 is associated with endocrine ...
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Lack of association between hOG ...
Recently, we read with great interest the article ‘‘The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis’’ published online in A ...
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Mothers’ pre-pregnancy BMI and ...
Previous studies have established that higher birthweight is associated with increased risk of breast cancer. However, the mechanisms underlying thi ...
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The influence of removal of pri ...
Recent studies have shown that the detection of circulating tumor cells (CTC) pre and postoperatively in the peripheral blood of primary breast canc ...
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The association of reproductive ...
Reproductive factors that influence breast cancer risk may also have an impact on survival, once the disease is diagnosed. In this study, 2,640 wome ...
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Well-done meat intake and meat- ...
Previous studies of the association of meat intake and meat-derived mutagen exposure with breast cancer risk have produced inconsistent results. We ...
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