Loss of heterozygosity analysis in malignant gliomas
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Loss of heterozygosity analysis ...
Despite recent advances in the diagnosis and treatment of glioblastomas, patient outcomes for these highly malignant tumors remain poor. Research in ...
317.01 KB
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Grade II oligodendroglioma loca ...
The presence of a primary central nervous system (CNS) neoplasm within the corpus callosum generally portends a grave prognosis. Common pathologies ...
592.16 KB
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Are we missing the mTOR target ...
Abnormalities in the PI3K/Akt/mTOR intracellular signalling pathway have been implicated in several forms of human cancer. The central component of ...
125.72 KB
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Detection of circulating tumor ...
Most assays to detect circulating tumor cells (CTCs) rely on EpCAM expression on tumor cells. Recently, our group reported that in contrast to other ...
610.66 KB
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Oral fluoropyrimidine may augme ...
The present preclinical study was designed to evaluate a new combination therapy comprised of the aromatase inhibitor anastrozole (ANA) and the oral ...
526.71 KB
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Detection and clinical relevanc ...
The factors determining the clinical relevance of disseminated tumor cells (DTC) in breast cancer patients are largely unknown. Here we compared the ...
390.51 KB
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A randomized, placebo-controlle ...
We hypothesized that exemestane (EXE) would reduce mammographic breast density and have unique effects on biomarkers of bone and lipid metabolism. ...
184.91 KB
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Socioeconomic inequalities in a ...
The associations of socioeconomic status (SES) and participation in the breast cancer screening program, as well as consequences for stage of diseas ...
361.88 KB
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A recombination-based method to ...
Many missense variants in BRCA1 are of unclear clinical significance. Functional and genetic approaches have been proposed for elucidating the clini ...
340.35 KB
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The association between IGF1 CA ...
Recently, we read with interest the article by Huang et al. [1]. They performed a meta-analysis of nine case–control studies (5,641 cases and 10,471 ...
102.40 KB
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Does the effect of weight lifti ...
The lymphedema diagnostic method used in descriptive or intervention studies may influence results found. The purposes of this work were to compare ...
184.18 KB
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Routine pathologic parameters c ...
OncotypeDXTM is an RT-PCR-based assay used to predict chemotherapy benefit in patients with estrogen receptor (ER) positive breast cancers. We were ...
450.68 KB
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Membrane localization of insuli ...
Recent studies have identified a role for insulin receptor substrate-2 (IRS-2) in promoting motility and metastasis in breast cancer. However, no pu ...
1.34 MB
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Circulating free DNA: a new sur ...
Despite progress made in the oncologic therapy, the prognosis of the patients with breast cancer is still limited by metastatic relapse often many y ...
144.84 KB
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Associations between polymorphi ...
We read with great interest the article by Yang et al. which investigated the associations between tumor necrosis factor-a (TNF-a) polymorphisms an ...
229.85 KB
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Traditional breast cancer risk ...
At least four major categories of invasive breast cancer have been reproducibly identified by gene expression profiling: luminal A, luminal B, HER2- ...
200.03 KB
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Different CHEK2 germline mutati ...
Germline mutations in BRCA1 were already linked to basal-like subtype of immunophenotypic molecular classification of breast cancer (BC). However, i ...
213.21 KB
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Single nucleotide polymorphisms ...
The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, ...
227.76 KB
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Detection of isolated ipsilater ...
Imaging diagnostic methods except for mammograms are not recommended for follow-up of postoperative breast cancer patients in order to detect small ...
203.50 KB
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Epithelial-mesenchymal transiti ...
Currently used methods to detect and enumerate circulating tumor cells (CTCs) rely on the expression of the epithelial cell adhesion molecule (EpCAM ...
261.29 KB
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Androgen receptor expression in ...
The androgen receptor (AR) has been shown to be of potential prognostic importance in retrospective cohorts. We evaluated immunohistochemical AR exp ...
633.43 KB
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Nodular fasciitis of the breast
Nodular fasciitis of the breast is a rare, benign, soft-tissue tumor that can clinically and radiologically mimic invasive ductal carcinoma. A 25-ye ...
261.50 KB
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Carotid Stenting for Restenosis ...
Introduction Restenosis after carotid endarterectomy (CEA) has been described in 8–19% of patients, 14–23% of whom become symptomatic. This study an ...
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Penetrating Atherosclerotic Ulc ...
We describe a case of endovascular treatment in a 64-year-old woman affected by a penetrating atherosclerotic ulcer (PAU) of the abdominal aorta wit ...
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Embolisation of the Gastroduode ...
Introduction The gastroduodenal artery (GDA) is usually embolised to avoid nontarget dispersal before yttrium-90 (Y90) radioembolisation to treat li ...
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