Williams-Beuren syndrome: historical aspects
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Williams-Beuren syndrome: histo ...
Williams syndrome, also known as Williams- Beuren syndrome (OMIM database entry 194050), is now known to be commonly associated with a hemizygous c ...
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Regulation of p53 Localization ...
The abundance and activity of p53 are regulated largely by ubiquitin ligases. Here we demonstrate a previously undisclosed regulation of p53 localiza ...
854.33 KB
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In vitro cytokine production by ...
The authors evaluated the ability of bone cement to modify the pro"le of pro-in#ammatory cytokines secreted by the immune cells. Peripheral blood mon ...
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Protein–polysaccharide interact ...
If the most important parameters affecting protein–polysaccharide interactions are now well documented, recent advances concern the structure-buildin ...
1.12 MB
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Molecular thermodynamics of pre ...
Using a simple theory for fluids and a simple theory for a solid, it is possible to construct a semi-quantitative correspondingstates phase diagram w ...
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DNA Polymerase ŋ , the Product ...
DNA polymerase (PolH) is the product of the xeroderma pigmentosum variant (XPV) gene and a well-characterized Y-family DNA polymerase for translesi ...
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Recent Progress in Functional G ...
With the completion and near completion of many malaria parasite genome-sequencing projects, efforts are now being directed to a better understanding ...
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Genomics of Fungal Disease Resi ...
Tomato (Solanum lycopersicum) is an important vegetable crop worldwide. Often times, its production is hindered by fungal diseases. Important fungal ...
290.98 KB
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A General Quantitative Genetic ...
Uncertainty about linkage phases of multiple single nucleotide polymorphisms (SNPs) in heterozygous diploids challenges the identification of specifi ...
295.99 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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Regulation of the DNA Damage Re ...
Damage to the genetic material can affect cellular function in many ways. Therefore, maintenance of the genetic integrity is of primary importance fo ...
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Evaluation of a Recombinant Rif ...
The possible role of the most abundant structural protein of Rift Valley fever virus (RVFV), the nucleocapsid protein (NP), in inducing protective im ...
310.29 KB
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Recent Advances in Intervention ...
Markovian regulatory networks constitute a class of discrete state-space models used to study gene regulatory dynamics and discover methods that bene ...
557.72 KB
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High PIB Retention in Alzheimer ...
Background: New in vivo amyloid PET imaging tracers, such as 11C-PIB, provide possibilities to deeper understand the underlying pathological processe ...
437.30 KB
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Pharmacological Characteristics ...
K201 is a 1,4-benzothiazepine derivative that is a promising new drug with a strong cardioprotective effect. We initially discovered K201 as an effec ...
350.78 KB
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Treatment with Imiquimod enhanc ...
Background: There is an urgent need to develop new innovative therapies for the control of advanced cancer. The combination of antigen-specific immun ...
874.24 KB
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The Arrestin Fold: Variations o ...
Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. ..-arrestins ...
دانلود 1
599.82 KB
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Rallying the Troops: Innate Muc ...
The mucosal surfaces of the gastrointestinal tract are constantly exposed to large quantities of commensal microbes and enteric pathogens. Highly sop ...
475.55 KB
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Cloning and characterization of ...
Background: The CHD7 (Chromodomain Helicase DNA binding protein 7) gene encodes a member of the chromodomain family of ATP-dependent chromatin remode ...
523.79 KB
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Alternative Splicing and Tumor ...
Alternative splicing is a key molecular mechanism for increasing the functional diversity of the eukaryotic proteomes. A large body of experimental d ...
399.79 KB
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Periostin as a Heterofunctional ...
Periostin (Postn) is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesi ...
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Oncogenomic Approaches in Explo ...
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signall ...
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Mitochondrial and Nuclear Genes ...
Although the observation of aerobic glycolysis of tumor cells by Otto v. Warburg had demonstrated abnormalities of mitochondrial energy metabolism in ...
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Functional and Clinical Evidenc ...
We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas ( ...
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Exploitation of Aspergillus nig ...
Filamentous fungi of the Aspergillus niger group are native soil saprophytic fungi. Industrial strains of this group have been extensively used for t ...
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