Economic evaluation of the 21-gene signature (Oncotype ...
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Economic evaluation of the 21-g ...
The 21-gene signature is validated as a good predictor of recurrence for lymph node-negative/positive, hormone receptor-positive, early-stage breast ...
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A combined analysis of genome-w ...
In an attempt to identify common disease susceptibility alleles for breast cancer, we performed a combined analysis of three genome-wide association ...
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A functional 277T>C polymorp ...
X-ray repair cross-complementing 1 (XRCC1) plays a critical role in base excision repair and genetic variations of XRCC1 may be associated with canc ...
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Asian ethnicity and breast canc ...
The distribution of breast cancer molecular subtypes has been shown to vary by race/ethnicity, highlighting the importance of host factors in breast ...
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Genetic variants in COX-2, non- ...
Chronic inflammation has been consistently associated with cancers of several sites, including the breast, and inhibition of inflammation through th ...
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RAD51 G135C polymorphism is ass ...
Several studies have investigated the associations between RAD51 G135C polymorphism and the susceptibility to breast cancer, but results have been ...
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One size does not fit all: qual ...
Adjuvant endocrine therapy for breast cancer is associated with significant improvements in disease-related outcomes. Five years of tamoxifen therap ...
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Disparities in breast cancer ch ...
Disparities in breast cancer stage and mortality by race/ethnicity in the United States are persistent and well known. However, few studies have ass ...
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Spectrum of BRCA1/2 point mutat ...
The distribution of BRCA1/2 germline mutations in breast/ovarian cancer (BC/OC) families varies among different populations. In the Chilean populati ...
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Lack of association between ATM ...
Epidemiological studies have evaluated the association between ATM C.1066-6T[G (IVS10-6T[G) mutation and breast cancer risk. However, the results re ...
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Effect of aspirin and other NSA ...
Aspirin and other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can inhibit aromatase activity and thus could selectively lower inciden ...
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Impact of treatment characteris ...
Pathological complete response (pCR) to neoadjuvant treatment correlates with outcome in breast cancer. We determined whether characteristics of neo ...
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Anastrozole and letrozole: an i ...
Previous studies have demonstrated that both anastrozole and letrozole are well tolerated. Letrozole suppresses estrogen to a greater degree than an ...
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Socioeconomic differences in su ...
There seem to be socioeconomically differences in survival for females with breast cancer, usually associated with a higher stage of disease. Howeve ...
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Concurrent use of tamoxifen wit ...
Concurrent use of tamoxifen and cytochrome P450 2D6 (CYP2D6) inhibitors, such as selective serotonin reuptake inhibitors, has been shown to decrease ...
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Evidence on the association bet ...
Several molecular epidemiological studies were conducted in recent years to evaluate the association between NQO1 Pro187Ser polymorphism and breast ...
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Association between polymorphis ...
Epidemiological studies have evaluated the association between ataxia telangiectasia mutated (ATM) gene polymorphisms and breast cancer risk. Howeve ...
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Phase I/II study of sorafenib w ...
We evaluated the use of sorafenib to overcome resistance to aromatase inhibitors (AIs) in patients with metastatic breast cancer who had disease rec ...
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Disseminated tumor cells: the m ...
Bone marrow DTC in breast cancer It is a tenet of breast cancer biology that patients with primary (Stages I–III) breast cancer can harbor residual ...
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The mammalian target of rapamyc ...
mTOR plays a key role in tumor cell cycle control, proliferation, and survival. RAD001 (everolimus) is a novel macrolide that inhibits mTOR and thus ...
دانلود 1
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Let-7a regulation of insulin-li ...
Expression of certain microRNA genes is regulated by DNA methylation, which in turn affects the activities of their downstream molecules. Our previo ...
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Vascular endothelial growth fac ...
A cross talk between tyrosine kinase receptors and mitogen-activated protein kinases (MAPKs) is proposed as involved in endocrine resistance. We wan ...
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Immunohistochemistry compared t ...
The purpose of this study is to compare immunohistochemistry (IHC) and cytosol-based assays for determination of estrogen receptor (ER) and predicti ...
دانلود 1
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Bilateral breast cancer: analys ...
There has been conflicting evidence on the impact of bilateral breast cancer (BBC) on the survival and management of patients. The objectives of thi ...
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Benefits of early and prolonged ...
Response to fulvestrant and survival in postmenopausal hormone-sensitive advanced breast cancer was investigated within a non-randomized, In-Practic ...
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