Renin and Prorenin Receptor in Hypertension: What’s New ...
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Renin and Prorenin Receptor in ...
The (pro)renin receptor, PRR, was initially characterized as a component of the renin-angiotensin system (RAS). PRR-bound renin and prorenin display ...
دانلود 1
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Dual-Acting Angiotensin Recepto ...
Lowering blood pressure by pharmacologic intervention reduces the incidence of cardiovascular events. Nevertheless, despite the widespread availabil ...
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The DASH Diet and Insulin Sensi ...
Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who ar ...
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Metabolic Syndrome: From the Ge ...
The metabolic syndrome (MS) constitutes a combination of underlying risk factors for an adverse outcome, cardiovascular disease. Thus, the clinical ...
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Genetics of Salt-Sensitive Hype ...
The assessment of salt sensitivity of blood pressure is difficult because of the lack of universal consensus on definition. Regardless of the variab ...
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Genetics of Hypertension and Ca ...
Blood pressure (BP), hypertension (HT) and cardiovascular disease (CVD) are common complex phenotypes, which are affected by multiple genetic and en ...
دانلود 2
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Catecholamine Storage Vesicles: ...
Hypertension is a complex trait with deranged autonomic control of the circulation. The sympathoadrenal system exerts minute-to-minute control over ...
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Dietary Fructose and Hypertensi ...
The association between fructose and increased blood pressure is still incompletely defined, because experimental studies have produced dissimilar c ...
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Epigenetics and Hypertension
Epigenetics refers to mechanisms for environment– gene interactions (mainly by methylation of DNA and modification of histones) that do not alter th ...
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Endogenous Ouabain: A Link Betw ...
The sodium pump, an ancestral enzyme with conserved ability to bind ouabain, plays a key role in salt conservation and is regulated by aldosterone a ...
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Obesity and the Kidney
Background and objectives Obesity-related glomerulopathy (ORG) is an increasing cause of end-stage renal disease, but evidence concerning the effect ...
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Combination HIV Prevention: Sig ...
No single HIV prevention strategy will be sufficient to control the HIV pandemic. However, a growing number of interventions have shown promise in p ...
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Pathogenesis of HIV in the Cent ...
HIV can infect the brain and impair central nervous system (CNS) function. Combination antiretroviral therapy (cART) has not eradicated CNS complica ...
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Coreceptors and HIV-1 Pathogene ...
The major HIV-1 coreceptors, CCR5 and CXCR4, mediate virus entry into CD4+ cells and are therefore a critical component of the HIV-1 life cycle. Al ...
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Point-of-Care Testing
The availability of rapid, point-of-care (POC) tests has significantly expanded the capacity of both developed and resource-constrained countries (R ...
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Alterations of the B-Cell Respo ...
While the hallmark of HIV-1 infection is the progressive depletion of CD4+ T cells, extensive B-cell dysfunction ensues that impairs the quality of ...
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Revisiting Immune Exhaustion Du ...
Chronic immune activation is a hallmark of HIV infection, yet the underlying triggers of immune activation remain unclear. Persistent antigenic stim ...
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IL28B Polymorphisms and Treatme ...
Recently, single-nucleotide polymorphisms near the IL28B gene have been identified as important in predicting treatment response and spontaneous cle ...
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Rational Guide to the Use of Er ...
Hepatitis C virus (HCV) infection is the leading reason for liver transplant in North America. Combination therapy with pegylated interferon and ri ...
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Management of Hepatitis C Antiv ...
Hepatitis C is one of the leading causes of liver disease in the United States, affecting more than 4 million individuals. The current treatment reg ...
دانلود 1
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HCV Eradication: Implications f ...
Hepatitis C virus (HCV) is a leading cause of liver-related death worldwide. The evolution of hepatitis C therapy has made serologic eradication of ...
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Update on Current Epidemiologic ...
Hepatitis C virus infection remains a leading cause of liver disease worldwide and is currently the principal reason for liver transplantation in th ...
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Extrahepatic Manifestations of ...
Hepatitis C virus (HCV) is the most common blood-borne infection in the United States and is a leading cause of chronic liver disease worldwide. Ext ...
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HCV Response-Guided Therapy: Sh ...
The treatment of chronic HCV has traditionally been for a fixed duration based on genotype. We now recognize that patients respond to treatment alon ...
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The Emerging Role of Histone De ...
T-cell lymphomas are an uncommon and heterogeneous group of non-Hodgkin lymphomas. Historically, therapies for these diseases have been borrowed fro ...
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