Clinicopathologic and molecular significance of phospho ...
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Clinicopathologic and molecular ...
Akt/PKB serine/threonine kinase is a leading signalling modulator for several cellular processes including metabolism, growth, proliferation and sur ...
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Inflammatory breast cancer: hig ...
Inflammatory breast cancer (IBC), the most lethal form of breast cancer, has characteristics linked to higher risk of contralateral breast cancer. H ...
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A gene expression signature ide ...
Prognosis of basal breast cancers is poor but heterogeneous. Medullary breast cancers (MBC) display a basal profile, but a favorable prognosis. We h ...
303.11 KB
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Concurrent use of tamoxifen wit ...
Concurrent use of tamoxifen and cytochrome P450 2D6 (CYP2D6) inhibitors, such as selective serotonin reuptake inhibitors, has been shown to decrease ...
207.15 KB
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A combined analysis of genome-w ...
In an attempt to identify common disease susceptibility alleles for breast cancer, we performed a combined analysis of three genome-wide association ...
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Randomized, double-blind compar ...
Near-infrared (NIR) fluorescence imaging has the potential to improve sentinel lymph node (SLN) mapping in breast cancer. Indocyanine green (ICG) is ...
319.06 KB
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Value of post-operative reasses ...
The NICE trial was designed to evaluate the possible benefits of adding epidermal growth factor receptor targeted therapy to neoadjuvant chemotherap ...
دانلود 1
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The association between IGF1 CA ...
IGF-I CA repeat polymorphisms have been reported to influence the risk for breast cancer in many studies; however, the results still remains controv ...
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Significant changes in dietary ...
The diagnosis of cancer can motivate survivors to alter their lifestyle habits. Healthcare providers need to be aware of what changes patients are l ...
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Improved survival of patients w ...
In this study, changes in prognosis for more than 8,000 patients with primary distant metastatic breast cancer were analyzed, using nation-wide data ...
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Significant differences among p ...
The National Comprehensive Cancer Network (NCCN) has published guidelines for hereditary breast and ovarian cancer syndrome (HBOCS) management. Litt ...
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Paraneoplastic polymyositis ass ...
The association of polymyositis and cancer was first described in 1916, the most frequent cancers being mammary and gynecological for women, broncho ...
347.50 KB
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Genetic variants in ultraconser ...
Ultraconserved elements (UCEs) are the most extreme representatives of conserved non-coding sequences. Recent studies have indicated thatUCEs are no ...
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No evidence for an association ...
Breast cancer represents a serious public health problem worldwide, for its high incidence, morbidity, mortality, and its high cost treatment. It is ...
142.15 KB
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High estrogen receptor expressi ...
One of the most controversial questions in early breast cancer treatment is the need of chemotherapy in patients with estrogen receptor positive dis ...
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Agonists and antagonists of GnR ...
Metastasis to bone is a frequent problem of advanced breast cancer. Particularly breast cancers, which do not express estrogen and progesterone rece ...
555.11 KB
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Metabotropic glutamate receptor ...
Metabotropic glutamate receptors are G-protein- coupled receptors normally expressed in the central nervous system where they mediate neuronal excit ...
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Role of PTEN promoter methylati ...
Tamoxifen (TAM) resistance is a serious clinical problem in the treatment of breast cancer. Here, we found that S-adenosylmethionine (SAM) and DNA m ...
725.64 KB
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Gene expression profile testing ...
As gene expression profile (GEP) testing for breast cancer may provide additional prognostic information to guide the use of adjuvant chemotherapy, ...
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A prognostic model for lymph no ...
model for a more precise prognosis of the risk of relapse is needed to avoid overtreatment of lymph node-negative breast cancer patients. A large de ...
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Correlation between docetaxel-i ...
Steroids and H2 blockers are commonly used as supportive care for taxane-containing chemotherapy, but they also affect docetaxel’s primary metaboliz ...
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Detection of aberrant promoter ...
Aberrant promoter methylation of genes is a common molecular event in breast cancer. Thus, DNA methylation analysis is expected to be a new tool for ...
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Insulin-like growth factor-1 re ...
Insulin-like growth factor-1 receptor (IGF1R) plays a key role in the initiation and progression of breast cancer. However, its prognostic relevance ...
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The role of topoisomerase IIa i ...
Topoisomerase IIa is not only a proliferation marker of tumor cells, but is also a target for anthracyclinebased chemotherapy. Both in vitro and in ...
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Targeting low molecular weight ...
Low molecular weight cyclin E (LMW-E) plays an important oncogenic role in breast cancer. LMWE, which is not found in normal tissue, can promote the ...
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