Role of PTEN promoter methylation in tamoxifen-resistan ...
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Role of PTEN promoter methylati ...
Tamoxifen (TAM) resistance is a serious clinical problem in the treatment of breast cancer. Here, we found that S-adenosylmethionine (SAM) and DNA m ...
725.64 KB
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Prediction of lymph node involv ...
The aim of this study was to investigate whether lymph node involvement in breast cancer is influenced by gene or miRNA expression of the primary tu ...
615.63 KB
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PH006, a novel and selective Sr ...
The central role of Src in tumor progression and metastasis has validated it as an attractive therapeutic target for the treatment of human breast c ...
642.90 KB
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The associations between two po ...
The association between single-nucleotide polymorphisms (SNPs) in the interleukin-10 (IL-10) gene promoter and breast cancer risk is still ambiguous ...
175.22 KB
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Acquisition of metastatic tissu ...
Biopsies of metastatic tissue are increasingly being performed. Bone is the most frequent site of metastasis in breast cancer patients, but bone rem ...
دانلود 2
166.25 KB
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Oral administration of benzyl-i ...
Benzyl-isothiocyanate (BITC) is a hydrolysis product of glucotropaeolin, a compound found in cruciferous vegetables, and has also been shown to have ...
663.85 KB
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MicroRNA profiles of healthy ba ...
In order to determine the microRNA expression pattern in normal basal and luminal breast epithelium and to analyze the relationship of this expressi ...
706.14 KB
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Estrogen receptor b causes a G2 ...
The role of estrogen receptor beta (ERb) in breast cancer is unclear. ERb is considered to have a protective role in breast cancer development based ...
430.08 KB
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Post-lumpectomy intracavitary r ...
Liposomes are recognized drug delivery systems with tumor-targeting capability. In addition, therapeutic or diagnostic radionuclides can be efficien ...
1.02 MB
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Presence of MMTV-like env gene ...
Park et al. 2010 (No evidence of MMTV-like env sequences in specimens from the Australian Breast Cancer Family Study, Breast Cancer Research and Tre ...
143.12 KB
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No significant association resu ...
We have read with great interest the article ‘‘No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-anal ...
104.89 KB
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Comprehensive CYP2D6 genotype a ...
The association between CYP2D6 genotype and outcome in breast cancer patients treated with adjuvant tamoxifen remains controversial. We assessed the ...
321.31 KB
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A 10-year follow-up of treatmen ...
We compare long-term outcomes in patients with node negative early stage breast cancer treated with breast radiotherapy (RT) without the axillary RT ...
336.35 KB
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Two novel variants in the 30UTR ...
For the majority of breast and/or ovarian cancer patients tested for BRCA1/2 genes, mutation screening of the coding regions remains negative. Micro ...
319.33 KB
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Poly(ADP-ribose) polymerase-1 m ...
Although poly(ADP-ribose) polymerase-1 (PARP1) inhibition is a recent promising therapy in breast cancer, PARP1 expression in this disease is not kn ...
307.72 KB
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A recombination-based method to ...
Many missense variants in BRCA1 are of unclear clinical significance. Functional and genetic approaches have been proposed for elucidating the clini ...
340.35 KB
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Gene expression array testing o ...
Archived formalin-fixed, paraffin embedded (FFPE) tissues constitute a vast, well-annotated, but underexploited resource for the molecular study of ...
302.55 KB
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A high prevalence of BRCA1 muta ...
The Bahamas is a group of islands in the Caribbean with a high incidence of early onset breast cancer. In isolated populations, the identification o ...
185.69 KB
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LFA-1 gene polymorphisms are as ...
The infiltrative duct carcinoma (IDC) is the most common malignant breast cancer in females and genetic factors appear to play a significant role in ...
دانلود 1
179.82 KB
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No evidence for an association ...
Breast cancer represents a serious public health problem worldwide, for its high incidence, morbidity, mortality, and its high cost treatment. It is ...
142.15 KB
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Vitamin D threshold to prevent ...
Aromatase inhibitor (AI)-associated arthralgia limits adherence to therapy in breast cancer. The pathophysiology may involve vitamin D status. We wi ...
250.60 KB
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Individual responses to chemoth ...
Differences in redox homeostatic control between cancer patients may underlie predisposition to drug resistance and toxicities. To evaluate interind ...
266.25 KB
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No association of polymorphisms ...
The human homolog of the Drosophila Scribble (SCRIB) tumor suppressor gene encodes a protein that regulates apical-basolateral polarity in mammalian ...
204.22 KB
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Glutathione S-transferase P1 Il ...
Glutathione S-transferase P1 (GSTP1) is involved in a wide range of detoxifying reactions. Any alteration in the structure, function, or expression ...
271.98 KB
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Polymorphic variants in TSC1 an ...
TSC1 acts coordinately with TSC2 in a complex to inhibit mTOR, an emerging therapeutic target and known promoter of cell growth and cell cycle progr ...
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