Prognostic factor analyses of m ...
Multiple myeloma (MM) survival plots usually display steeper initial and shallower subsequent slopes reflecting differences in disease biology and l ...
Phase II fludarabine and cyclop ...
Indolent non-follicular non-Hodgkin lymphomas (INFL) are a heterogenous subset whose treatment has been poorly investigated. In this context we have ...
A study on nm23-H1 expression i ...
In our previous study on nm23-H1 expression with diffuse large B-cell lymphoma (DLBCL), we found that patients with positive nm23-H1 had significant ...
Limited role of interim PET/CT ...
Positron emission tomography (PET) has been found useful in monitoring response to treatment of malignant lymphoma. We investigated the ability of ...
The importance of a sub-region ...
The gene RAI was originally described as an inhibitor of RelA/p65 subunit of nuclear factor ƒبB (NF.ƒبB). Here, we analyse the association between g ...
CXCR4 expression on transplante ...
Expression of the chemokine receptor CXCR4 by haematopoietic stem cells (HSCs) is believed to influence the process of these cells پehomingپf back t ...
Seven-year response to imatinib ...
The purpose of our study is to compare the 7-year response to imatinib monotherapy as an initial treatment and re-treatment in Chinese patients with ...
Random skin biopsy and bone mar ...
Intravascular lymphoma (IVL) is a rare type of extranodal lymphoma in which the lymphoma cells proliferate exclusively in the lumina of small vessel ...
Hypoxia-inducible factors in ma ...
Aberrant activation of phosphoinositide-3 kinase/ Akt (PI3K/Akt) and mammalian target of rapamycin (mTOR) signaling is implicated in the pathogenesi ...
Resveratrol increases rate of a ...
In this study, we attempted to assess the interactions of resveratrol, a natural compound present in various plant species, with the purine analogue ...
Primary bone marrow diffuse lar ...
Diffuse large cell lymphoma involving bone marrow is not uncommon, but primary, de novo, bone marrow diffuse large B cell lymphoma (DLBCL) is rare. ...
Secondary central nervous syste ...
Secondary central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) includes an isolated CNS relapse or CNS involvement with ...
Indoleamine 2,3-dioxygenase in ...
Indoleamine 2,3-dioxygenase (IDO) exerts immunomodulatory effects due to enzymatic activities catalyzing the essential amino acid L-tryptophan. IDO ...
Thrombospondin-1 (TSP-1) in pri ...
Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm showing aberrant bone marrow remodeling with increased angiogenesis, progressiv ...
Expression of myelopoiesis-asso ...
The microRNA/miR deregulation in BCR-ABLnegative myelodysplastic-myeloproliferative neoplasms (MDS/MPN) is not known. Myelopoiesis-associated miR-1 ...
The role of routine imaging pro ...
Despite improved initial therapies, a subgroup of patients with aggressive non-Hodgkin (A-NHL) and Hodgkin lymphomas (HL) will relapse after first r ...
CLIPI: a new prognostic index f ...
Indolent primary cutaneous B cell lymphomas (PCBCL) generally have a good prognosis, but they often relapse leading in some cases to extracutaneous ...
Long-term outcome of hemizygous ...
The transcriptional regulator GATA1 is crucially involved in megakaryocytopoiesis and erythropoiesis. Mutations of the gene which is located on the ...
Prevalence of H63D, S65C, and C ...
Hereditary HFE Hemochromatosis is an inherited disorder of iron metabolism that results from mutations in the HFE gene. Almost all patients with her ...
High prevalence of hepatitis B ...
We performed a large case–control study (3,932 cases, 15,562 controls) to investigate the association of hepatitis B virus (HBV) and hepatitis C vir ...
Overexpression of the EZH2, RIN ...
Epigenetics refers to the study of clonally inherited changes in gene expression without accompanying genetic changes. Previous research on the epig ...
Long-term follow-up of patients ...
Prior to introduction of imatinib mesylate, the median survival of chronic myeloid leukemia (CML) patients was approximately 60 months and the stand ...
CYP2B6 gene single nucleotide p ...
CYP2B6 is a highly variable and polymorphic cytochrome P450 enzyme which plays a vital role in the degradation of some endogenous metabolites, xenob ...
Sickle-cell disease and malaria ...
Sickle-cell disease (SCD) patients are at high risk of developing malaria which is a major contributor to morbidity andmortality in this disease. In ...
Severe congenital neutropenia i ...
We have analysed a family with nine congenital neutropenia patients in four generations, several of which we have studied in a long-term follow-up o ...