New neuropathological findings ...
Unverricht–Lundborg disease (EPM1A), also known as Baltic myoclonus, is the most common form of progressive myoclonic epilepsy. It is inherited as a ...
Cell stress induces TDP-43 path ...
TDP-43 has been implicated in the pathogenesis of amyotrophic lateral sclerosis and other neurodegenerative diseases. Here we demonstrate, using ne ...
Cholinergic imbalance in the mu ...
Hippocampal pathology was shown to be extensive in multiple sclerosis (MS) and is associated with memory impairment. In this post-mortem study, we ...
The spinal muscular atrophy mou ...
Spinal muscular atrophy (SMA) is a neurodegenerative disease resulting from decreased levels of survival motor neuron 1 (SMN1) protein. Reduced SMN1 ...
Factors affecting Ab plasma lev ...
Previous studies of Ab plasma as a biomarker for Alzheimer’s disease (AD) obtained conflicting results. We here included 715 subjects with baseline ...
The cerebellar component of Fri ...
Lack of frataxin in Friedreich’s ataxia (FRDA) causes a complex neurological and pathological phenotype. Progressive atrophy of the dentate nucleus ...
Widespread non-central nervous ...
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder generally presenting with intention tremor and gait ...
Postsynaptic degeneration as re ...
Impairment of synaptic plasticity underlies memory dysfunction inAlzheimer’s disease (AD). Molecules involved in this plasticity such as PSD-95, a m ...
Enhancement of endogenous neuro ...
Cerebral ischemia stimulates endogenous neurogenesis. However, the functional relevance of this phenomenon remains unclear because of poor survival ...
Vasculitis-like neuropathy in a ...
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease with variable involvement of other systems. A pathogenetic role of immune-mediat ...
Macrophage migration inhibitory ...
Macrophage migration inhibitory factor (MIF), which inhibits apoptosis and promotes angiogenesis, is expressed in cancers suppressing immune surveil ...
Peroxisomal alterations in Alzh ...
In Alzheimer’s disease (AD), lipid alterations are present early during disease progression. As some of these alterations point towards a peroxisoma ...
Globular glial tauopathies (GGT ...
A number of recent studies have described cases with tau-positive globular oligodendroglial inclusions (GOIs) and such cases have overlapping pathol ...
Comparison of SHR, WKY and Wist ...
Spontaneously hypertensive rats (SHR) and its counterpart, the Wistar-Kyoto rats (WKY), are probably the most often used animal model of ADHD. Howev ...
Antecedents of ADHD: a historic ...
The concept of ADHD has evolved gradually and still carries some traces of its origins. The idea of uncontrolled behaviour as a medical problem aros ...
A pilot study: differential eff ...
To examine the effects of methylphenidate- OROS (MPH-OROS) on working memory (WM) and attention functions in children with attention-deficit hypera ...
Childhood obesity and parental ...
ADHD prevalence has risen in parallel with rising prevalence of pregnancy smoking and childhood obesity. The objective was to determine the epidemio ...
ADHD and comorbid conduct probl ...
Attention-deficit/hyperactivity disorder (ADHD) is a common child and adolescent disorder that is associated with negative outcomes (e.g., emotional ...
Neurocognitive correlates of ad ...
We established a neuropsychological testing profile among Turkish adults presenting with ADHD controlling for general intelligence and comorbid psyc ...
Olfactory and gustatory sensiti ...
Recently, research on olfactory functions in attention-deficit/hyperactivity disorder (ADHD) has become prominent, whereas gustation has never been ...
Mothers of children with attent ...
This study focuses on mothers of children diagnosed with attention deficit/hyperactivity disorder (ADHD) and sets out (1) to characterize dimensions ...
Long-term open-label response t ...
A three-year open-label study of atomoxetine in adults with ADHD followed two multicenter, double-blind trials. In the double-blind trials, female g ...
An exploration of the associati ...
Intra-individual variability of the characteristics of children with attention-deficit hyperactivity (ADHD) may reflect compromised glial energy sup ...
Potential cognitive endophenoty ...
Endophenotypes are neurobiological markers cosegregating and associated with illness. These biomarkers represent a promising strategy to dissect ADH ...
No evidence for association bet ...
Noradrenergic neurotransmission influences executive functions, attentional performance, and general alertness, involving neuronal networks affected ...