Advances in the understanding o ...
Receptors for the Fc fragment of immunoglobulin G (FccRs) are important molecules not only to mediate and control the effectors’ functions of IgG an ...
High mobility group box 1 induc ...
Recently, it was discovered that high mobility group box chromosomal protein 1 (HMGB1) acts as a potent pro-inflammatory cytokine that is released i ...
Plasminogen activator inhibitor ...
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of autoantibodies against nuclear autoantigens as ...
b1,4-galactosyltransferase-I in ...
b1,4-galactosyltransferase-I (b1,4-GalT-I), which is one of the best-studied glycosyltransferases, plays a key role in the synthesis of selectin lig ...
Association of increased serum ...
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by abnormal production of autoantibodies and proinflammatory cytokines. A ...
A T-cell-based enzyme-linked im ...
Anti-tumour necrosis factor-a (TNF-a) therapy brought new hopes for treating rheumatic diseases but also increased the risk of infection, including ...
Establishment of airway eosinop ...
Eosinophilic bronchitis (EB) is a useful tool for studying airway hyperresponsiveness (AHR), but an exact EB animal model is lacking. Our objective ...
Glycosylation of mucins present ...
It is suggested that gastric mucins, and in particular some specific glycan structures that can act as carbohydrate receptors, are involved in the i ...
B7-H4 expression in various tum ...
B7-H4, a new member of the B7 family, may participate in the negative regulation of cell-mediated immunity, while aberrant B7-H4 expression is detec ...
Effect of allogeneic bone marro ...
Primary biliary cirrhosis (PBC) is a slowly progressive autoimmune disease of unknown mechanism. We established a PBC animal model by injecting C57B ...
Comparison between clinical sig ...
Gastric cancer (GC) is a second most common cause of cancer-related death and represents an inflammation- driven malignancy. It has been suggested t ...
Lipopolysaccharide (LPS) of Hel ...
The epithelium of the intestinal tract is exposed to a variety of genotoxic agents, both exogenous and endogenous, that can injure nuclear and mitoc ...
Hepcidin expression in anemia o ...
Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency ...
DNA amplification on chromosome ...
Colorectal cancer is a leading cause of cancer deaths worldwide. Genetic markers involved in prognosis of colorectal cancer are still being elucidat ...
Wnt/beta-Catenin pathway in hum ...
Gliomas are the most common primary intracranial tumors. Understanding the molecular basis of gliomas’ progression is required to develop more effec ...
Complete correction of anemia b ...
Insulin resistance and anemia secondary to erythropoietin deficiency characterize patients with endstage kidney disease. In a cross-sectional analys ...
Anemia correction by erythropoi ...
Little is known about the effect of anemia correction with erythropoietin (EPO) on B-type natriuretic peptide (BNP) levels, NYHA class, and hospital ...
Gene delivery of soluble vascul ...
Intra-plaque angiogenesis plays an important role in the development of atherosclerotic plaque. Vascular endothelial growth factor (VEGF) is a major ...
Survivin -31C/G polymorphism an ...
Gastric cancer, despite its decline in incidence, remains a public health problem worldwide, especially in Brazil, where higher incidence indexes ar ...
Serum prealbumin (transthyretin ...
Low serum protein and albumin are considered to significantly associate with malnutrition, impaired functional status, poor outcome, and mortality. ...
Role of serum adiponectin level ...
Adiponectin possesses anti-inflammatory and insulin-sensitizing properties. Little is known about the role of adiponectin in hepatitis-C-related liv ...
Hypocholesterolemia is associat ...
The oxidative stress levels in plasma and hemolysate and cholesterol levels in plasma of sickle cell anemia patients, carriers and controls were eva ...
Rapid and sensitive allele-spec ...
Point mutations in the kinase domain of BCRABL were described in 40–90% of patients with chronic myeloid leukemia (CML) resistant to Imatinib. We he ...
Vardenafil, an inhibitor of pho ...
Decreased production and/or impaired action of nitric oxide (NO) play a role in the pathogenesis of atherosclerotic cardiovascular disease and erect ...
Orbital pseudotumor in a child: ...
Orbital pseudotumor is a benign, idiopathic, non-infectious and non-neoplastic clinical syndrome characterized by the presence of an inflammatory ma ...