FOXO3a nuclear localisation is associated with good pro ...
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FOXO3a nuclear localisation is ...
Oestrogen receptor (ER)-positive breast cancer (BC) constitutes a heterogeneous group of tumours with regard to outcome and response to therapy. Acc ...
512.31 KB
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Pathways mediating the effects ...
Invasion and metastasis of aggressive breast cancer cells are the final and fatal steps during cancer progression. Clinically, there are still limit ...
426.11 KB
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Development of 95-gene classifi ...
Our aim was to develop an accurate diagnostic system using gene expression analysis by means of DNA microarray for prognosis of node-negative and es ...
501.78 KB
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High immunogenic potential of p ...
As pre-existent immunity might be a reflection of an emerging anticancer response, the demonstration of spontaneous T-cell responses against tumor a ...
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An evaluation of the clinical s ...
Studies in mice have shown that thymicderived CD4? CD25? regulatory T cells (T reg; FOXP3? lymphocytes) inhibit an antitumour immune response. Addi ...
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S-adenosylhomocysteine hydrolas ...
Epigenetic abnormalities including abnormal histone methyltransferase activity contribute to breast cancer pathogenesis. An example is over expressi ...
612.15 KB
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Bone mineral density and risk o ...
To determine if higher bone mineral density (BMD) is a risk factor for breast cancer in women age 50 years and older. 37,860 women C50-year old with ...
176.17 KB
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RAD51 G135C polymorphism is ass ...
Several studies have investigated the associations between RAD51 G135C polymorphism and the susceptibility to breast cancer, but results have been ...
176.52 KB
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VEGF 936C>T polymorphism and ...
Vascular endothelial growth factor (VEGF) is one of the most potent endothelial cell mitogens and plays an important role in angiogenesis. Many publ ...
159.33 KB
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Defining breast cancer prognosi ...
The objective of this study is to define the survival outcomes associated with distinct molecular phenotypes defined by immunohistochemical staining ...
217.63 KB
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Breast cancers in U.S. residing ...
South Asians from India and Pakistan represent one of the fastest growing immigrant populations in the US, yet there are limited data assessing brea ...
323.55 KB
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No evidence for an association ...
ABCC11 is an ATP-binding cassette transporter responsible for the transport of a diverse range of lipophilic compounds. A single nucleotide polymorp ...
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Identification and characteriza ...
BAF57 is a core subunit present in all mammalian SWI/SNF ATP-dependent chromatin remodeling complexes, which regulates important biological processe ...
534.23 KB
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Genome-wide copy number alterat ...
Genomic copy number alterations (CNA) are common in breast cancer. Identifying characteristic CNAs associated with specific breast cancer subtypes i ...
دانلود 1
483.95 KB
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Mutational characterization of ...
Understanding how cancer genes are mutated in individual tumors is an important issue with potential clinical and therapeutic impact. This is especi ...
دانلود 1
286.95 KB
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The associations between two po ...
The association between single-nucleotide polymorphisms (SNPs) in the interleukin-10 (IL-10) gene promoter and breast cancer risk is still ambiguous ...
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Co-expression of SNAIL and TWIS ...
Epithelial mesenchymal transition (EMT) plays an important role in the development of metastases. One of the hallmarks of EMT is loss of E-cadherin ...
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Overexpression of ligase defect ...
E6-associated protein (E6-AP) is a dual function protein. It acts as an E3 ubiquitin-protein ligase enzyme and coactivator of steroid hormone recept ...
1.36 MB
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Hematogenous and lymphatic tumo ...
Tumor cell dissemination in bone marrow (BM) and lymph nodes is considered an important step in systemic disease progression and is associated with ...
400.88 KB
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bc-GenExMiner: an easy-to-use o ...
Gene prognostic meta-analyses should benefit from breast tumour genomic data obtained during the last decade. The aim was to develop a user-friendly ...
907.25 KB
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Unliganded progesterone recepto ...
Whether the presence of steroid receptors in luminal breast cancers renders them resistant to taxanes remains uncertain. Here we assess the role of ...
730.96 KB
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First-line bevacizumab in combi ...
Despite extensive evaluation of first-line bevacizumab- containing therapy in randomized trials in locally recurrent/metastatic breast cancer (LR/mB ...
325.02 KB
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Ultrasonography- and/or mammogr ...
Background It is very important to excise ductal carcinoma in situ (DCIS) with sufficient margins to prevent local recurrence. We describe the exper ...
341.80 KB
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Anastrozole can cause severe hy ...
65-year-old woman on anastrozole treatment because of a recurrent breast cancer developed hypercalcaemia and increased parathyroid hormone (PTH) lev ...
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Is lymphovascular invasion degr ...
Background Patients who achieve pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) have favorable disease-free survival rates. ...
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