Osteoclastogenesis and arthritis
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Osteoclastogenesis and arthriti ...
There is emerging interest for osteoclasts as key players in the erosive and inflammatory events leading to joint destruction in chronic arthritis. ...
223.42 KB
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Advances in the understanding o ...
Receptors for the Fc fragment of immunoglobulin G (FccRs) are important molecules not only to mediate and control the effectors’ functions of IgG an ...
363.80 KB
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High mobility group box 1 induc ...
Recently, it was discovered that high mobility group box chromosomal protein 1 (HMGB1) acts as a potent pro-inflammatory cytokine that is released i ...
3.04 MB
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Plasminogen activator inhibitor ...
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of autoantibodies against nuclear autoantigens as ...
223.65 KB
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b1,4-galactosyltransferase-I in ...
b1,4-galactosyltransferase-I (b1,4-GalT-I), which is one of the best-studied glycosyltransferases, plays a key role in the synthesis of selectin lig ...
537.10 KB
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Association of increased serum ...
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by abnormal production of autoantibodies and proinflammatory cytokines. A ...
173.78 KB
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A T-cell-based enzyme-linked im ...
Anti-tumour necrosis factor-a (TNF-a) therapy brought new hopes for treating rheumatic diseases but also increased the risk of infection, including ...
197.41 KB
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Establishment of airway eosinop ...
Eosinophilic bronchitis (EB) is a useful tool for studying airway hyperresponsiveness (AHR), but an exact EB animal model is lacking. Our objective ...
501.34 KB
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Glycosylation of mucins present ...
It is suggested that gastric mucins, and in particular some specific glycan structures that can act as carbohydrate receptors, are involved in the i ...
373.30 KB
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B7-H4 expression in various tum ...
B7-H4, a new member of the B7 family, may participate in the negative regulation of cell-mediated immunity, while aberrant B7-H4 expression is detec ...
427.66 KB
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Effect of allogeneic bone marro ...
Primary biliary cirrhosis (PBC) is a slowly progressive autoimmune disease of unknown mechanism. We established a PBC animal model by injecting C57B ...
698.09 KB
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Comparison between clinical sig ...
Gastric cancer (GC) is a second most common cause of cancer-related death and represents an inflammation- driven malignancy. It has been suggested t ...
268.13 KB
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Lipopolysaccharide (LPS) of Hel ...
The epithelium of the intestinal tract is exposed to a variety of genotoxic agents, both exogenous and endogenous, that can injure nuclear and mitoc ...
383.16 KB
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Hepcidin expression in anemia o ...
Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency ...
401.27 KB
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DNA amplification on chromosome ...
Colorectal cancer is a leading cause of cancer deaths worldwide. Genetic markers involved in prognosis of colorectal cancer are still being elucidat ...
294.00 KB
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Wnt/beta-Catenin pathway in hum ...
Gliomas are the most common primary intracranial tumors. Understanding the molecular basis of gliomas’ progression is required to develop more effec ...
481.85 KB
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Complete correction of anemia b ...
Insulin resistance and anemia secondary to erythropoietin deficiency characterize patients with endstage kidney disease. In a cross-sectional analys ...
206.58 KB
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Anemia correction by erythropoi ...
Little is known about the effect of anemia correction with erythropoietin (EPO) on B-type natriuretic peptide (BNP) levels, NYHA class, and hospital ...
229.80 KB
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Gene delivery of soluble vascul ...
Intra-plaque angiogenesis plays an important role in the development of atherosclerotic plaque. Vascular endothelial growth factor (VEGF) is a major ...
601.74 KB
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Survivin -31C/G polymorphism an ...
Gastric cancer, despite its decline in incidence, remains a public health problem worldwide, especially in Brazil, where higher incidence indexes ar ...
153.15 KB
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Serum prealbumin (transthyretin ...
Low serum protein and albumin are considered to significantly associate with malnutrition, impaired functional status, poor outcome, and mortality. ...
178.71 KB
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Role of serum adiponectin level ...
Adiponectin possesses anti-inflammatory and insulin-sensitizing properties. Little is known about the role of adiponectin in hepatitis-C-related liv ...
260.52 KB
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Hypocholesterolemia is associat ...
The oxidative stress levels in plasma and hemolysate and cholesterol levels in plasma of sickle cell anemia patients, carriers and controls were eva ...
173.22 KB
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Rapid and sensitive allele-spec ...
Point mutations in the kinase domain of BCRABL were described in 40–90% of patients with chronic myeloid leukemia (CML) resistant to Imatinib. We he ...
296.63 KB
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Vardenafil, an inhibitor of pho ...
Decreased production and/or impaired action of nitric oxide (NO) play a role in the pathogenesis of atherosclerotic cardiovascular disease and erect ...
264.63 KB
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