Body weight and risk of breast ...
Obesity is an established risk factor for postmenopausal breast cancer in the general population. However, it is still unclear whether this associat ...
Chemotherapy for metastatic bre ...
Although new chemotherapeutic drugs for metastatic breast cancer (MBC) have been approved over the past decade, it is unclear whether this has chang ...
Associations between mammograph ...
Although high mammographic density is a risk factor for postmenopausal breast cancer, its etiology remains unclear. We examined whether serum and di ...
Different gene expressions are ...
The goal of this study was to determine whether gene expression differences exist between inflammatory breast cancers (IBC) and T stage-matched non- ...
A variant affecting miRNAs bind ...
Disruption of the circadian rhythm has been reported to increase the risk of breast cancer. A single nucleotide polymorphism (SNP) rs2305160 in Neur ...
Age-related variation in the re ...
Multiple past studies have reported a reduced risk of breast cancer-related mortality (BCM) in relation to pre-diagnostic use of hormone therapy (HT ...
Potent CYP2D6 Inhibiting drugs ...
Endoxifen, the most active metabolite of the prodrug tamoxifen, is produced by cytochrome P450 CYP2D6. Breast cancer patients treated with tamoxifen ...
Periodontal disease may associa ...
The main purpose was to evaluate the association between periodontal disease and the incidence of breast cancer in a prospective study of 3273 rando ...
Defining breast cancer prognosi ...
The objective of this study is to define the survival outcomes associated with distinct molecular phenotypes defined by immunohistochemical staining ...
A BRCA2 mutation incorrectly ma ...
Inherited mutations in the tumor suppressor genes BRCA1 and BRCA2 predispose carriers to breast and ovarian cancer. The authors have identified a mu ...
Lack of an association between ...
Several studies have investigated the associations between AURKA T91A polymorphism and the susceptibility to breast cancer, but the results have bee ...
Randomized phase III trial of a ...
Adjuvant cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) have proven highly effective in rapidly proliferating breast cancer (RPBC). It has ...
Variation in genes coding for A ...
AMP-activated protein kinase (AMPK) is an energy sensing/signalling intracellular protein which is activated by an increase in the cellular AMP:ATP ...
Role of ethnic variations in TN ...
TNF-a and -b, the multi-functional pro-inflammatory cytokines, are known to play important roles in both tumor progression and destruction based on ...
Possible risk modifications in ...
Manganese superoxide dismutase (MnSOD) has been identified as an important scavenger of reactive oxygen species (ROS), which can cause oxidative str ...
Germline mutations in BRCA1 and ...
Three mutations in BRCA1 (185delAG, 5382InsC) and BRCA2 (6174delT) predominate among high risk breast ovarian cancer Ashkenazi Jewish families, with ...
Association between polymorphis ...
Trinucleotide repeat containing 9 (TNRC9) is a gene located at chromosome 16q12. Although of an uncertain function, it is a newly described risk fac ...
No evidence of excess breast ca ...
This analysis addresses risk of breast cancer among women in BRCA-positive families who test negative for the family mutation. We compared the numbe ...
Association between patient rep ...
Neurotoxicity is a common side-effect during taxane therapy. The prevalence and severity of long-term neurotoxicity following therapy is unknown. Th ...
CAG repeat length polymorphism ...
We analyzed the length of the CAG repeats of the androgen receptor gene in Indian women with breast cancer, and compared the data with that of other ...
Increased risk of contralateral ...
Breast cancer (BC) survivors are at increased risk of second cancers. Obesity is commonly recognized as a risk factor of BC in postmenopausal period ...
VEGF 936C>T polymorphism and ...
Vascular endothelial growth factor (VEGF) is one of the most potent endothelial cell mitogens and plays an important role in angiogenesis. Many publ ...
Effects of breast cancer surger ...
We examined the impact of surgical treatments (breast-conserving surgery [BCS], mastectomy alone, mastectomy with reconstruction) and surgical side- ...
Preventable breast cancer is po ...
Breast cancer incidence has markedly increased in Western countries for reasons that are not entirely understood. We characterized periodic and age- ...
Ixabepilone plus capecitabine i ...
Patients with metastatic breast cancer (MBC) previously treated with anthracyclines and taxanes often have decreased performance status secondary to ...