Adiponectin, cardiovascular dis ...
Over the past decade, adiponectin has been a subject of interest in many fields of medicine. The effect of adiponectin in metabolism and inflammatio ...
Can bisphosphonates play a role ...
In patients with chronic kidney disease (CKD) renal osteodystrophy, in the form of either low- or highturnover bone disease, is quite common. While ...
Longitudinal study of bone mine ...
Children with idiopathic hypercalciuria (IH) may have a reduced bone mineral density (BMD), which could impact on bone health in adulthood. There is ...
Bilateral renal artery stenosis ...
Epidermal nevus syndrome is a rare congenital sporadic neuro-ectodermic disorder, characterized by the presence of epidermal nevi in association wit ...
Surgical management of vesicour ...
Vesicoureteral reflux (VUR) is the most common uropathy affecting children. Compared to children without VUR, those with VUR have a higher rate of p ...
Optimizing treatment strategies ...
The letter by Davin and colleagues in this issue of Pediatric Nephrology on the long-term efficacy of plasma therapy (PT) in atypical haemolytic ura ...
Cyclosporine A vs. methylpredni ...
Knowledge about how to treat severe Henoch– Schِnlein nephritis (HSN) is scarce. The aimof our study is to compare cyclosporine A (CyA) and methylpr ...
Urine IL-8 concentrations in in ...
Urine IL-8 concentrations are known to be elevated in urinary tract infection (UTI), as well as in vesicoureteral reflux (VUR) even in the absence o ...
Renal FMD may not confer a fami ...
Renal fibromuscular dysplasia (FMD) can cause hypertension, and previous reports suggest that FMD is familial. We hypothesized that, in families con ...
New developments in the treatme ...
A large number of new studies on the treatment of systemic lupus erythematosus (SLE) have recently been or are about to be published. Unfortunately, ...
CKD-MBD after kidney transplant ...
Successful kidney transplantation corrects many of the metabolic abnormalities associated with chronic kidney disease (CKD); however, skeletal and c ...
Urinary calcium and uric acid e ...
Urolithiasis is relatively common in children, and identifiable predisposing factors for stone formation, including metabolic and structural derange ...
A 10-year-old with proteinuria ...
The seat of ultra filtration of all the fluid in the human body is the glomerulus. The normal glomerular basement membrane is composed of a triple h ...
Evaluation of the highly sensit ...
The immune response against alloantigens involves the production of antibodies and development of T-cell immunity. Recipients sensitized to HLA anti ...
Hypertensive crisis in children
Hypertensive crisis is rare in children and is usually secondary to an underlying disease. There is strong evidence that the renin-angiotensin syste ...
Distinct metalloproteinase excr ...
Metalloproteinase-2 (MMP-2) and metalloproteinase- 9 (MMP-9) degrade type IV collagen, and represent important tissue remodeling enzymes in several ...
Clinical presentation and metab ...
Although pediatricians are frequently confronted with patients presenting urolithiasis symptoms without obvious stones, the syndrome of occult uroli ...
Long-term renal function under ...
In a paper byWaters and Licht published recently in Pediatric Nephrology, eculizumab is presented as the emerging drug to replace plasma exchange (P ...
Genetic testing in renal diseas ...
A revolution is happening in genetics! The decoding of the first genome in 2003 was a large international collaborative effort that took about 13 ye ...
The PDGF family in renal fibros ...
The platelet-derived growth factor (PDGF) family plays an important role in embryonic development, malignancy, wound healing, atherosclerosis, and f ...
Bartter- and Gitelman-like synd ...
Salt-losing tubulopathies with secondary hyperaldosteronism (SLT) comprise a set of well-defined inherited tubular disorders. Two segments along the ...
Is fibroblast growth factor 23 ...
Fibroblast growth factor 23 (FGF23) is a novel hormone produced by bone with known functions to regulate urinary phosphate excretion, as well as vit ...
Transition from pediatric to ad ...
The number of young patients graduating from paediatric to adult renal care has progressively increased due to improved management resulting in pati ...
The origin of interstitial myof ...
Chronic kidney diseases (CKD), independent of their primary cause, lead to progressive, irreversible loss of functional renal parenchyma. Renal path ...
Hypertension in infancy: diagno ...
Advances in the ability to identify, evaluate, and care for infants with hypertension, coupled with advances in the practice of Neonatology, have le ...