SOX2 gene expression in normal ...
The SOX gene family encodes a large group of transcription factors that are strongly involved in the normal human development and malignancies. Huma ...
Effect of IL-1b and TNF-a polym ...
So far, a number of association studies have focused on the effect of polymorphisms in IL-1b and TNF-a genes on the susceptibility to gastric cancer ...
Single oligoarray-based detecti ...
The most important mutation associated with Multiple Endocrine Neoplasia type 2B (MEN 2B) is the change of thymine to cytosine in codon 918 of exon ...
Orbital pseudotumor in a child: ...
Orbital pseudotumor is a benign, idiopathic, non-infectious and non-neoplastic clinical syndrome characterized by the presence of an inflammatory ma ...
Vardenafil, an inhibitor of pho ...
Decreased production and/or impaired action of nitric oxide (NO) play a role in the pathogenesis of atherosclerotic cardiovascular disease and erect ...
Rapid and sensitive allele-spec ...
Point mutations in the kinase domain of BCRABL were described in 40–90% of patients with chronic myeloid leukemia (CML) resistant to Imatinib. We he ...
Hypocholesterolemia is associat ...
The oxidative stress levels in plasma and hemolysate and cholesterol levels in plasma of sickle cell anemia patients, carriers and controls were eva ...
Role of serum adiponectin level ...
Adiponectin possesses anti-inflammatory and insulin-sensitizing properties. Little is known about the role of adiponectin in hepatitis-C-related liv ...
Serum prealbumin (transthyretin ...
Low serum protein and albumin are considered to significantly associate with malnutrition, impaired functional status, poor outcome, and mortality. ...
Survivin -31C/G polymorphism an ...
Gastric cancer, despite its decline in incidence, remains a public health problem worldwide, especially in Brazil, where higher incidence indexes ar ...
Gene delivery of soluble vascul ...
Intra-plaque angiogenesis plays an important role in the development of atherosclerotic plaque. Vascular endothelial growth factor (VEGF) is a major ...
Anemia correction by erythropoi ...
Little is known about the effect of anemia correction with erythropoietin (EPO) on B-type natriuretic peptide (BNP) levels, NYHA class, and hospital ...
Complete correction of anemia b ...
Insulin resistance and anemia secondary to erythropoietin deficiency characterize patients with endstage kidney disease. In a cross-sectional analys ...
Wnt/beta-Catenin pathway in hum ...
Gliomas are the most common primary intracranial tumors. Understanding the molecular basis of gliomas’ progression is required to develop more effec ...
DNA amplification on chromosome ...
Colorectal cancer is a leading cause of cancer deaths worldwide. Genetic markers involved in prognosis of colorectal cancer are still being elucidat ...
Hepcidin expression in anemia o ...
Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency ...
Lipopolysaccharide (LPS) of Hel ...
The epithelium of the intestinal tract is exposed to a variety of genotoxic agents, both exogenous and endogenous, that can injure nuclear and mitoc ...
Effect of allogeneic bone marro ...
Primary biliary cirrhosis (PBC) is a slowly progressive autoimmune disease of unknown mechanism. We established a PBC animal model by injecting C57B ...
B7-H4 expression in various tum ...
B7-H4, a new member of the B7 family, may participate in the negative regulation of cell-mediated immunity, while aberrant B7-H4 expression is detec ...
Glycosylation of mucins present ...
It is suggested that gastric mucins, and in particular some specific glycan structures that can act as carbohydrate receptors, are involved in the i ...
Establishment of airway eosinop ...
Eosinophilic bronchitis (EB) is a useful tool for studying airway hyperresponsiveness (AHR), but an exact EB animal model is lacking. Our objective ...
A T-cell-based enzyme-linked im ...
Anti-tumour necrosis factor-a (TNF-a) therapy brought new hopes for treating rheumatic diseases but also increased the risk of infection, including ...
Association of increased serum ...
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by abnormal production of autoantibodies and proinflammatory cytokines. A ...
b1,4-galactosyltransferase-I in ...
b1,4-galactosyltransferase-I (b1,4-GalT-I), which is one of the best-studied glycosyltransferases, plays a key role in the synthesis of selectin lig ...
Plasminogen activator inhibitor ...
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of autoantibodies against nuclear autoantigens as ...