Dyslipidemia in children with C ...
Dyslipidemia has been shown to be a risk factor for increased cardiovascular morbidity and mortality in adult patients with chronic kidney disease ( ...
Cardiorespiratory fitness in yo ...
Limited knowledge exists on cardiorespiratory fitness (CR fitness) in adults having a renal transplant (Rtx) during childhood. Our aim was to assess ...
Maintenance therapy with mycoph ...
Rituximab (RTX) has a significant steroidsparing effect in children with steroid-dependent nephrotic syndrome (SDNS). However, patients are likely t ...
Nephrotic syndrome in infancy c ...
Nephrotic syndrome in the first year of life (NSFL) is a heterogeneous group of disorders, the management of which is supportive, as most patients d ...
Insufficient protection by Neis ...
Sirs, Spurred by the reported spectacular results of eculizumab treatment in atypical hemolytic uremic syndrome (aHUS) due to aberrations in the co ...
The role of molecular genetics ...
Familial microscopic hematuria (MH) of glomerular origin represents a heterogeneous group of monogenic conditions involving several genes, some of w ...
Epidemiology of chronic kidney ...
In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available ep ...
Weight or body surface area dos ...
Although prednisone is the treatment of choice for nephrotic syndrome (NS) in childhood, the dosing regimen varies between 60 mg/m2/day, as recommen ...
Rhabdomyolysis: pathogenesis of ...
Rhabdomyolysis refers to the breakdown of skeletal muscle due to either a physical, biological, or toxic injury that leads to leakage of muscle cont ...
A patient with polyuria and hyd ...
The case demonstrates the importance of assessing NDI and hydronephrosis separately. Hydronephrosis is a recognised complication of primary NDI and ...
Heart ventricular activation in ...
Children with chronic kidney disease (CKD) are affected by cardiovascular complications, including disturbances in the intraventricular conduction s ...
The impact of vesicoureteral re ...
Vesicoureteral reflux (VUR) is a heterogeneous disease and its management remains one of the most controversial topics in pediatrics. Management opt ...
Postnatal trends in creatinemia ...
To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betametha ...
Neurological development in 21 ...
Few studies have focused on the neurodevelopment of infants on peritoneal dialysis (PD). Infants are the most demanding patient group on PD and thus ...
Posterior reversible encephalop ...
Posterior reversible encephalopathy syndrome (PRES) was originally used to describe a reversible, predominantly posterior leukoencephalopathy in pat ...
Why is hypercalciuria absent at ...
We try to explain why hypercalciuria is absent at diagnosis in some children with an ATP6V1B1 mutation. A 5-month-old girl presented with distal ren ...
Vitamin D deficiency is associa ...
Vitamin D deficiency is common in adult renal transplant recipients, but data in children are scarce. Vitamin D is shown to have multiple effects on ...
Ciliogenesis in normal human ki ...
Ciliogenesis in developing and post-natal human kidneys appears to influence cell proliferation and differentiation, apico–basal cell polarity, and ...
Acute glomerulonephritis and ac ...
Sirs, We read with great interest the letter by Jain et al. regarding a 14-year-old boy with postinfectious glomerulonephritis following infection ...
Wnt signaling and renal medulla ...
The renal medulla, the inner compartment of the metanephric kidney, plays vital roles in the regulation of body water, electrolyte homeostasis, and ...
Exchange transfusion as rescue ...
Sirs, Acute renal failure (ARF) affects 8–24% of babies admitting to neonatal intensive care units [1]. Dialysis or hemofiltration is the treatment ...
Not ready for prime time: alisk ...
Sirs, In the past, children were often excluded from studies of new medications, resulting in insufficient efficacy and safety data [1]. While this ...
A case of post-infectious glome ...
Sirs, It was fascinating to read the recent publication by Ghiggeri et al. [1] that haematuria can be a prodrome for H1N1 infection in children whi ...
Xenopus pronephros development— ...
Kidney development is a multi-step process where undifferentiated mesenchyme is converted into a highly complex organ through several inductive even ...
Acetyl salicylic acid treatment ...
Antenatal Bartter syndrome is an autosomal recessive disorder caused by loss-of-function mutations in genes encoding for the renal outer medullary p ...