Molecular and clinical analysis of glioblastoma with an ...
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Molecular and clinical analysis ...
The genetic and clinical features of glioblastoma with an oligodendroglial component (GBMO), pathologically defined as anaplastic oligo-astrocytoma ...
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Quantitative digital assessment ...
Recent reports have suggested an important clinical role for hypermethylation of the O6-methylguanine- DNA-methyltransferase (MGMT) promoter in pati ...
554.00 KB
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Detection of IDH1 mutation in h ...
Isocitrate dehydrogenase 1 (IDH1) mutations have recently been identified as early and frequent genetic alterations in astrocytomas, oligodendroglio ...
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Loss of heterozygosity analysis ...
Despite recent advances in the diagnosis and treatment of glioblastomas, patient outcomes for these highly malignant tumors remain poor. Research in ...
317.01 KB
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Persistent roles of signal tran ...
We previously reported that retrovirally transduced platelet-derived growth factor-B (PDGFB) in glial progenitors of the rat cerebral white matter, ...
1.19 MB
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Precise comparison of protoporp ...
Photodynamic diagnosis is used during glioma surgery. Although some studies have shown that the spectrum of fluorescence was efficient for precise t ...
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O6-Methylguanine DNA methyltran ...
Expression of the O6-methylguanine-DNA methyltransferase (MGMT) gene has been shown to correlate with clinical outcomes in patients with glioblastom ...
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Non-promoter hypermethylation o ...
Zygote arrest 1 (ZAR1) is a novel maternal-effect gene of crucial importance during the oocyte-to-embryo transition. Comprehensive methylation analy ...
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Subependymal giant cell astrocy ...
A 49-year-old woman presented with a history of periodic episodes of nausea and vomiting starting in 2006. In June 2009, the patient lost consciousn ...
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Quantitative analysis of matrix ...
Malignant gliomas are characterized by their invasiveness and angiogenesis. Matrix metalloproteinases (MMPs) degrade extracellular matrix and create ...
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New insights into glioma classi ...
In glioma, mutations in the isocitrate dehydrogenase 1 and 2 (IDH1/2) genes have been receiving attention. IDH1/2 mutations are frequently found in ...
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Epithelioid glioblastoma change ...
A 55-year-old man was admitted to our hospital complaining of left hemiparesis. Magnetic resonance imaging (MRI) showed a smooth ring-like enhanced ...
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Epstein–Barr virus (EBV)-associ ...
The frequency and clinical features of Epstein– Barr virus (EBV)-associated primary central nervous system lymphoma (PCNSL) in elderly patients were ...
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A miR-21 inhibitor enhances apo ...
MicroRNAs (miRNAs) are small noncoding RNAs that take part in diverse biological processes by suppressing target gene expression. Elevated expressio ...
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Rhabdoid glioblastoma in a chil ...
Rhabdoid glioblastoma is a rare type of glioblastoma characterized by cells resembling rhabdomyoblasts. Several reports have identified its aggressi ...
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Spontaneous regression of multi ...
We present a case of spontaneous regression of multicentric pilocytic astrocytoma with cerebrospinal fluid (CSF) dissemination without neurofibromat ...
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Clinicopathological and immunoh ...
The aim of this study was to summarize the clinicopathological features and the histological diversity of choroid plexus tumors and to examine the e ...
1.16 MB
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A case of atypical teratoid/rha ...
Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant tumor that mostly occurs in early childhood and has poor prognosis despite aggressive therap ...
2.61 MB
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Olig2 is useful in the differen ...
A 42-year-old woman had suffered from headaches since April 2009. Computed tomography revealed a tumor with marked calcification in the left frontal ...
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Brain metastases exhibit gross ...
Candidate genes involved in metastasis to the brain require investigation. In the present study, the adenomatous polyposis coli (APC) gene was analy ...
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Histopathological study of spin ...
Although the histogenesis of meningiomas remains unclear, it is believed that arachnoid cells are the most likely origin of this type of neoplasm. F ...
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Pineal mixed germ cell tumor wi ...
Intracranial germ cell tumors (GCTs) typically affect children and adolescents. We here report on a 59-year-old male patient presenting with diplopi ...
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Metabolic assessment of monofoc ...
Monofocal acute inflammatory demyelination (MAID), which is observable by CT and MRI as a wellenhanced mass lesion with prominent perifocal edema, i ...
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Primary central nervous system ...
A 37-year-old man, a hepatitis B virus carrier due to mother-to-child transmission, had a medical examination in September 2008 in nearby hospitals ...
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Infratentorial brain metastases ...
Three pediatric patients with infratentorial metastatic non-epithelial malignant brain tumors were successfully treated by radical surgical resectio ...
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