The Massachusetts General Hospital guide to clinical cancer genetics
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Daniel C Chung; Daniel A Haber; Massachusetts General Hospital.
- ناشر : New York ; London : Springer
- چاپ و سال / کشور: 2010
- شابک / ISBN : 0387938443
Description
Basic principles of cancer genetics Principles of Cancer Genetic Counseling and Genetic Testing Genetics of Hereditary Breast Cancer Surgical management of Hereditary Breast and Ovarian Cancer Hereditary colon cancer: Colonic Polyposis Syndromes Hereditary colon cancer: Lynch Syndrome Hereditary Pancreatic Cancer Hereditary Diffuse Gastric Cancer Familial Renal Cell Cancers and Pheochromocytomas Familial Atypical Mole Melanoma (FAMM) Syndrome Multiple Endocrine Neoplasia Pediatric malignancies: Retinoblastoma and Wilms' tumor Neurofibromatosis and Schwannomatosis The Hap Map project and low penetrance cancer susceptibility alleles Somatic genetic alterations and implications for targeted therapies in cancer (GIST, CML, Lung cancer)
This text reviews current knowledge in the genetics of many hereditary cancers. It offers practical guidelines for the use of genetic testing, cancer screening and surveillance, and prophylactic surgery. It also discusses promising targeted therapeutic agents
