Molecular pathology of lung diseases

Molecular pathology of lung diseases

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Dani S Zander; et al
  • ناشر : New York, NY : Springer
  • چاپ و سال / کشور: 2008
  • شابک / ISBN : 978-0-387-72429-4

Description

Genes, gene products, and transcription factors -- Receptors, signaling pathways, cell cycle, and DNA damage repair -- Cell adhesion molecules -- Apoptosis and cell death: relevance to lung -- Roles of mutation and epimutation in the development of lung disease -- Bioinformatics and omics -- General approach to molecular pathology -- Applications of molecular tests in anatomic pathology -- Polymerase chain reaction and reverse transcription-polymerase chain reaction -- Array comparative genomic hybridization in pathology -- Loss of heterozygosity in lung diseases -- In situ hybridization: principles and applications for pulmonary medicine -- Proteomics -- Animal models of lung disease -- Tissue culture models -- Molecular oncogenesis of lung cancer -- Genetic susceptibility -- Prognostic markers -- Pulmonary angiogenesis in neoplastic and nonneoplastic disorders -- Lung cancer stem cells. Gene therapy approaches for lung cancer -- Response to conventional therapy and targeted molecular therapy -- Environmental agents in lung and pleural neoplasms -- Viral oncogenesis -- Adenocarcinoma and its precursor lesions -- Molecular pathology of squamous cell carcinoma and its precursors -- Molecular pathology of large cell carcinoma and its precursors -- Small cell carcinoma -- Neuroendocrine carcinomas and precursors -- Pulmonary lymphomas -- Posttransplantation lymphoproliferative disorder -- Unusual benign and malignant neoplasms of lung: molecular pathology -- Primary versus metastatic cancer: gene expression profiling -- Diffuse malignant mesothelioma: genetic pathways and mechanisms of oncogenesis of asbestos and other agents that cause mesotheliomas -- Molecular pathology of pediatric tumors of the lung -- Basis of susceptibility to lung infection -- Molecular pathology of viral respiratory diseases. Molecular pathology of rickettsial lung infections -- Bacteria -- Immunopathology of tuberculosis -- Molecular pathology of fungal lung infection -- Parasites -- Inflammation -- Oxidants and antioxidants -- Epithelial repair and regeneration -- Fibrogenesis -- Stem cells in nonneoplastic lung disorders -- Gene therapy in nonneoplastic lung disorders -- Smoking-related lung diseases -- Heritable a1-antitrypsin deficiency -- Asthma -- Cystic fibrosis -- Pulmonary organogenesis and developmental abnormalities -- Genetic abnormalities of surfactant metabolism -- Usual interstitial pneumonia -- Sarcoidosis: are there sarcoidosis genes? -- Histiocytic diseases of the lung -- Pulmonary arterial hypertension -- Immunopathology of pulmonary vasculitides -- Asbestosis and silicosis.
This major work, complete with 150 illustrations, many of them in color, bridges the gap between clinical pulmonary pathology and basic molecular science. Through a highly visual approach that features an abundance of tables and diagrams, the book offers a practical disease-based overview.
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