Molecular and Biochemical Toxicology.
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Robert C Smart; Ernest Hodgson
- ناشر : Hoboken : John Wiley & Sons
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9780470285244
Description
MOLECULAR AND BIOCHEMICAL TOXICOLOGY; CONTENTS; Preface; Contributors; 1. Molecular and Biochemical Toxicology: Definition and Scope; 2. Overview of Molecular Techniques in Toxicology: Genes and Transgenes; 3. Toxicogenomics; 4. Proteomics; 5. Metabolomics; 6. Bioinformatics; 7. Immunochemical Techniques in Toxicology; 8. Cellular Techniques; 9. Structure, Mechanism, and Regulation of Cytochromes P450; 10. Phase I Metabolism of Toxicants and Metabolic Interactions; 11. Phase I--Toxicogenetics; 12. Phase II--Conjugation of Toxicants; 13. Regulation and Polymorphisms in Phase II Genes.
An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals. Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismic levels. Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic toxicology, significant changes have been made t.