Molecular and cellular biology of neuroprotection in the CNS
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Christian Alzheimer
- ناشر : New York : Kluwer Academic / Plenum Publishers
- چاپ و سال / کشور: 2003
- شابک / ISBN : 9780585440347
Description
I. Neuronal Cell Death : Overview of Basic Mechanisms -- 1. Excitatory amino acid neurotoxicity / T. Gillessen ... [et al.] -- 2. Neuronal survival and cell death signaling pathways / R.S. Morrison ... [et al.] -- 3. Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system / G. Stoll -- 4. Cellular and molecular determinants of glial scar formation / A. Logan, M. Berry -- II. Ion Channels, Receptors and Signaling Pathways -- 5. Na+ channels and Ca2+ channels of the cell membrane as targets of neuroprotective substances / C. Alzheimer -- 6. Intracellular Ca2+ handling / R.J. Sayer -- 7. Neuroprotective activity of metabotropic glutamate receptor ligands / P.J. Flor ... [et al.] -- 8. A role for glutamate transporters in neurodegenerative diseases / D. Trotti -- 9. Purines and neuroprotection / T.W. Stone -- 10. Heat shock proteins and neuroprotection / M.A. Yenari -- III. Neurotrophic Factors as Neuroprotective Agents -- 11. Neurotrophins / G. Dechantl, H. Neumann -- 12. Fibroblast growth factors and neuroprotection / C. Alzheimer, S. Werner -- 13. TGF-betas and their roles in the regulation of neuron survival / K. Unsicker, K. Krieglstein -- 14. Vascular endothelial growth factor / H.H. Marti -- IV. Advances in Drug Delivery to CNS Neurons -- 15. Blood-brain barrier drug targeting enables neuroprotection in brain ischemia following delayed intravenous administration of neurotrophins / W.M. Pardridge -- 16. Invasive drug delivery / U. Blomer ... [et al.] -- V. Neuroprotective strategies in animal and in vitro models of neuronal damage -- 17. Ischemia and stroke / M. Endres, U. Dirnagl -- 18. Neuroprotective strategies in Alzheimer's disease / C. Behl.
