Enzyme- and transporter-based drug-drug Interactions : progress and future challenges
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : K Sandy Pang; A David Rodrigues; Raimund M Peter
- ناشر : New York : Springer
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9781441908407
Description
Preface; Contents; Contributors; About the Editors; Part I Determinants of Drug ADME; 1 Enzymatic Basis of Phase I and Phase II Drug Metabolism; References; 2 Transporters: Importance in Drug Absorption, Distribution, and Removal; References; 3 ADME Pharmacogenetics and Its Impact on DrugDrug Interactions; References; 4 Impact of Nuclear Receptors CAR, PXR, FXR, and VDR, and Their Ligands On Enzymes and Transporters; References; 5 Impact of Physiological Determinants: Flow, Binding, Transporters and Enzymes on Organ and TotalBody Clearances; References.
Preface; Contents; Contributors; About the Editors; Part I Determinants of Drug ADME; 1 Enzymatic Basis of Phase I and Phase II Drug Metabolism; References; 2 Transporters: Importance in Drug Absorption, Distribution, and Removal; References; 3 ADME Pharmacogenetics and Its Impact on DrugDrug Interactions; References; 4 Impact of Nuclear Receptors CAR, PXR, FXR, and VDR, and Their Ligands On Enzymes and Transporters; References; 5 Impact of Physiological Determinants: Flow, Binding, Transporters and Enzymes on Organ and TotalBody Clearances; References.
