Regulation of gene expression : molecular mechanisms
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Gary H Perdew; John P Vanden Heuvel; Jeffrey M Peters
- ناشر : Totowa, N.J. : Humana Press
- چاپ و سال / کشور: 2006
- شابک / ISBN : 9781588292650
Description
Part I. Gene Expression Control at the mRNA Level John P. Vanden Heuvel Chapter 1. Overview Chapter 2. Messenger RNA Accumulation Chapter 3. Transcript Profiling Chapter 4. Transcriptional Regulation of Gene Expression Chapter 5. Posttranscriptional Processing of Messenger RNA Study Questions References Part II. Regulation of Protein Levels and Transcription Factor Function Gary H. Perdew Chapter 1. Overview Chapter 2. Protein Synthesis and Turnover Chapter 3. Proteomics Chapter 4. Determination of Protein-Protein Interactions and the Motifs That Mediate Them Chapter 5. Posttranslational Modifications Chapter 6. Dissection of Signaling Pathways Study Questions References Part III. Use of Transgenic and Knockout Mice to Study Gene Regulation Jeffrey M. Peters Chapter 1. Overview Chapter 2. Production of Transgenic Animals Chapter 3. Knockout Animals Chapter 4. Isolation of Cells and Cell Lines From Transgenic and Knockout Animals Study Questions References Index
Presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. This title explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals.
