Hemorrhagic radiation gastritis successfully treated with repeated intra-arterial steroid infusions
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Kazuhito Kawata Yoshimasa Kobayashi Kenichi Souda Kinya Kawamura Yurimi Takahashi Hidenao Noritake Shinya Watanabe Tomoyuki Suehiro Mi
- چاپ و سال / کشور: 2011
Description
Intra-arterial steroid infusion therapy has previously been shown to be effective for inflammatory bowel disease; however, few cases in which it has been used for the treatment of hemorrhagic radiation gastritis have been reported. We report the case of a 70-year-old Japanese man with hemorrhagic radiation gastritis induced by radiation therapy for para-aortic lymph node metastases of hepatocellular carcinoma. Two months after completing radiation therapy, acute persistent bleeding occurred in the gastric irradiation area. Although argon plasma coagulation was performed five times over a month, the bleeding continued and the patient showed persistent anemia that required 50 units of blood transfusion. Finally, the patient was given intra-arterial steroid infusions through the right gastric artery and the right gastroepiploic artery. After three intraarterial steroid infusions, the melena stopped, and the anemia no longer progressed. Hemorrhagic radiation gastritis was successfully treated with repeated intra-arterial steroid infusions through the regional vessels to the gastric mucosa. Repeated intra-arterial steroid infusions could be a clinically useful option for the treatment of intractable bleeding from radiation gastritis.
Clin J Gastroenterol (2011) 4:34–38 Received: 25 May 2010 / Accepted: 9 November 2010 / Published online: 10 December 2010 Springer 2010
