High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: can underestimation be predicted?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Pavel Crystal & Arifa Sadaf & Karina Bukhanov & David McCready & Frances O’Malley & Thomas H. Helbich
- چاپ و سال / کشور: 2010
Description
Objectives To evaluate the frequency of diagnosis of highrisk lesions at MRI-guided vacuum-assisted breast biopsy (MRgVABB) and to determine whether underestimation may be predicted. Methods Retrospective review of the medical records of 161 patients who underwent MRgVABB was performed. The underestimation rate was defined as an upgrade of a high-risk lesion at MRgVABB to malignancy at surgery. Clinical data, MRI features of the biopsied lesions, and histological diagnosis of cases with and those without underestimation were compared. Results Of 161 MRgVABB, histology revealed 31 (19%) high-risk lesions. Of 26 excised high-risk lesions, 13 (50%) were upgraded to malignancy. The underestimation rates of lobular neoplasia, atypical apocrine metaplasia, atypical ductal hyperplasia, and flat epithelial atypia were 50% (4/8), 100% (5/5), 50% (3/6) and 50% (1/2) respectively. There was no underestimation in the cases of benign papilloma without atypia (0/3), and radial scar (0/2). No statistically significant differences (p>0.1) between the cases with and those without underestimation were seen in patient age, indications for breast MRI, size of lesion on MRI, morphological and kinetic features of biopsied lesions. Conclusions Imaging and clinical features cannot be used reliably to predict underestimation at MRgVABB. All highrisk lesions diagnosed at MRgVABB require surgical excision
Eur Radiol (2011) 21:582–589 DOI 10.1007/s00330-010-1949-6 Received: 5 June 2010 / Revised: 25 July 2010 / Accepted: 30 July 2010 / Published online: 14 September 2010
