A better state of ART improving antiretroviral regimens to increase global access to HIV treatment
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Matthew Barnhart1* and James Shelton2
- چاپ و سال / کشور: 2011
Description
With 5.2 million people already receiving antiretroviral therapy (ART) in low and middle-income countries and 33.4 million people estimated to be living with HIV globally, there is an urgent need to develop better antiretroviral (ARV) regimens that are less costly and less complex to implement than the current standard of care. We think it is technically possible to develop such improved regimens soon, and discuss some illustrative examples of how new ARVs and treatment simplification approaches might simultaneously improve outcomes and dramatically reduce costs. Such regimens would: 1) include new ARVs that are more tolerable, durable, and inexpensive to manufacture; 2) contain a reduced number of ARVs; and/or 3) be amenable to directly observed dosing on a weekly or a monthly-basis. However, success will not only require technical solutions, but also good will and mechanisms to foster collaboration within the international community. Therefore, we also suggest a few priority actions that interested parties can take to help expedite the widespread availability of better ARV regimens.
Journal of AIDS and HIV Research Vol. 3(4), pp. 71-78, April 2011 Available online http:// academicjournals.org/JAHR ISSN 2141-2359 ©2011 Academic JournalsAccepted 04 March, 2011
