مقایسه ژل سیلیکون و عصاره پیاز برای زخم های بعد از جراحی Randomised comparison of silicone gel and onion extract gel for post-surgical scars

Introduction Surgical wound healing without noticeable scarring is an important aspect of cosmesis. Surgical scars can also cause pain, itching, discomfort, contracture, and other functional impairment (Niessen et al. 1999; Shaffer et al. 2002). The subjective opinion of patients regarding the surgical scar often constitutes the standard for judging the success or failure of the procedure (Rosio 1994). Various treatment options exist for treating hypertrophic scars and keloids, including intralesional steroid injection, dermabrasion, pressure therapy, surgical excision, radiotherapy, cryotherapy, pulsed dye laser, and carbon dioxide laser ablation (English and Shenefelt 1999; Mustoe et al. 2002; Shaffer et al. 2002; Widgerow et al. 2009). However, these treatments often require multiple visits and have limited success. Therefore, prevention and early recognition of hypertrophic scar and keloid formation in surgical wounds are very important in determining cosmetic outcomes. There are commercially available, topical scar emollients for the prevention of surgical scarring. The current market in scar emollient has divided into silicone gel (Chan et al. 2005; Chernoff et al. 2007) and onion extract gel (Chung et al. 2006; Chanprapaph et al. 2012). Despite their popularity, data demonstrating the efficacy of these scar emollients are lacking. Furthermore, there is no comparative study of silicone gel and onion extract gel for making new surgical scars less distinct. We therefore conducted this randomised controlled trial to compare the efficacy of silicone gel and onion extract gel on surgical wounds. We also compared patient compliance and adverse effect between the two topical gels.